Evidence map›Paper›PMID 39510737›Full record

ReviewObstetrics and gynecology clinics of North America2024

Primary Ovarian Insufficiency, Bone Health, and Other Outcomes in Adolescents.

Danielle T Cipres, Catherine M Gordon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Obstetrics and gynecology clinics of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Danielle T CipresDivision of Gynecology, Department of Surgery, Boston Children's Hospital, 333 Longwood Avenue, 5th Floor, Boston, MA 02115, USA; Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: Danielle.Cipres@childrens.harvard.edu.
Catherine M GordonDivision of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, NICHD Office of the Clinical Director, 10 CRC, Room 5-2583, 10 Center Drive, MSC 1109, Bethesda, MD 20892, USA.

Funding

NICHD Office of the Clinical DirectorZIDHD009016 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GORDON, CATHERINE · 2022 to 2025
$42.4M
Intramural NIH HHS ZID HD009016
6 · The paper itself

Abstract

Adolescents with primary ovarian insufficiency (POI) frequently present with arrested pubertal development or amenorrhea. Early evaluation of menstrual irregularities can avoid a delayed diagnosis. There are various genetic, autoimmune, and iatrogenic causes of POI, although most of the cases will not have an identified cause. Prompt initiation of hormone replacement therapy will restore developmentally appropriate pubertal progression, establishment of menses, and optimization of bone and cardiovascular health. The diagnosis of POI is often unexpected and life-altering for an adolescent and has broad health and psychosocial implications that are best approached with empathy, educational resources, and engagement of multidisciplinary specialists.

Indexed as

Primary Ovarian InsufficiencyAdolescentAmenorrheaBone DensityFemaleHormone Replacement TherapyHumansPubertyAdolescenceBone healthEstrogen therapyFertility preservationGonadal toxicityHypogonadismPrimary ovarian insufficiencyPubertal induction

Identifiers

PMID39510737
PMCPMC11566969

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.