Evidence map›Paper›PMID 39510515›Full record

ArticleJMIR research protocols2024

Assessing the Safety, User Acceptability, Dissemination, and Reach of a Comprehensive Web-Based Resource on Medications for Opioid Use Disorder (MOUD Hub): Protocol for a Development and Usability Study.

Melanie Jane Nicholls, Alexandra Almeida, Justin Castello, David Grelotti, Bianca Daugherty, Donny Gann, Karen Lenyoun, Sharon Trillo-Park, Annick Borquez

Abstract read
In one paragraph

Article in JMIR research protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melanie Jane NichollsCollege of Health and Human Services, San Diego State University, San Diego, CA, United States.ORCID 0000-0001-6169-9968
Alexandra AlmeidaPrograma de Computação Científica, FIOCRUZ, Rio de Janeiro, Brazil.ORCID 0000-0003-2092-5070
Justin CastelloUniversity Health Services, University of California, Berkeley, Berkeley, CA, United States.ORCID 0009-0007-8555-6655
David GrelottiDepartment of Medicine, University of California, San Diego, La Jolla, CA, United States.ORCID 0000-0002-9044-1314
Bianca DaughertyDepartment of Occupational Therapy, Colorado State University, Fort Collins, CO, United States.ORCID 0009-0002-3967-3205
Donny GannStone Soup Counseling, Baltimore, MD, United States.ORCID 0009-0000-8211-560X
Karen LenyounSchool of Public Health, University of California, La Jolla, San Diego, CA, United States.ORCID 0009-0001-6884-7211
Sharon Trillo-ParkDepartment of Medicine, University of California, San Diego, La Jolla, CA, United States.ORCID 0009-0005-0282-7815
Annick BorquezDepartment of Medicine, University of California, San Diego, La Jolla, CA, United States.ORCID 0000-0002-6033-9837

Funding

Real-time prediction of emerging drug use epidemics in the United StatesDP2DA049295 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BORQUEZ, ANNICK · 2019 to 2019
$2.4M
NIDA NIH HHS DP2 DA049295
6 · The paper itself

Abstract

backgroundMedications for opioid use disorder (MOUD), such as methadone and buprenorphine, are the gold standard for opioid use disorder (OUD) treatment. Owing to various barriers, MOUD access and retention are low in the United States. The internet presents a digital solution to mitigate barriers, but a comprehensive and reliable resource is lacking. We present a user-friendly, web-based resource, the MOUD Hub, that provides reliable information on MOUD.

objectiveThis study aims to assess the safety, acceptability, feasibility of dissemination, and reach of the MOUD Hub using focus groups and advertising on 1 key search engine and 1 social media platform.

methodsThis protocol describes the development of the MOUD Hub and the descriptive observational feasibility study that will be undertaken. The MOUD Hub uses motivational interviewing principles to guide users through the stages of change. The website provides evidence-based information from national health and substance use agencies, harm reduction organizations, and peer-reviewed literature. First, pilot focus groups with 10 graduate students who have lived experience with OUD will be conducted to provide feedback on safety concerns. Then, focus groups with 20-30 potential MOUD Hub users (eg, people with OUD with and without MOUD experience, friends and family, and health care providers) will be conducted to assess safety, acceptability, reach, and usability. Data will be analyzed using inductive thematic analysis. The website will be advertised on Google and MOUD-specific Reddit forums to assess dissemination, reach, and user acceptability based on the total user volume, sociodemographic characteristics, pop-up survey responses, and 1-year engagement patterns. This information will be collected through Google Analytics. Potential differences between users from Google and Reddit will be assessed.

resultsThe MOUD Hub will be launched in January 2025. Data collected from 5 focus groups (approximately 30-40 participants) will be used to improve the website before launching it. There is no target sample size for the second stage of the study as it aims to assess dissemination feasibility and reach. Data will be collected for a year, analyzed every 3 months, and used to improve the website.

conclusionsThe MOUD Hub offers an innovative theory-based approach, tailored to people with OUD and their family and friends, to increase access to and retention in MOUD treatment in the United States and provides broader harm reduction resources for those not currently in a position to receive treatment or those at risk of resuming illicit opioid use. Findings from this feasibility phase will serve to better tailor the MOUD Hub. After modifying the website based on our findings, we will use a randomized controlled trial to assess its efficacy in increasing MOUD access and retention, contributing to growing research on web-based interventions for OUD. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/57065.

Indexed as

Feasibility StudiesFocus GroupsInternetOpioid-Related DisordersBuprenorphineHumansInformation DisseminationMethadoneOpiate Substitution TreatmentUnited StatesBuprenorphineMethadonedigital healthdigital interventionmedications for opioid use disordermotivational interviewingopioid use disorderstages of changesubstance use

Identifiers

PMID39510515
PMCPMC11582488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.