ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2025
Endoscopic Sedation Type During FLIP Panometry Does Not Significantly Impact FLIP Motility Classification Relative to Manometry.
Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Functional Lumen Imaging Probe (EndoFLIP) in Upper Gastrointestinal Disorders: Current Evidence, Clinical Applications, and Future Perspectives.Diseases (Basel, Switzerland) · 2026Review
- Machine Learning Clustering Identifies Achalasia-Spectrum Phenotypes in Distal Esophageal Spasm.Journal of neurogastroenterology and motility · 2026Article
- The Role of Functional Lumen Imaging Probe (FLIP) in Addition to High-Resolution Manometry and Timed Barium Esophagram in Treated Achalasia Patients With Persistent or Recurrent Symptoms.Neurogastroenterology and motility · 2026Observational
- Artificial Intelligence and FLIP Panometry-Automated Classification of Esophageal Motility Patterns.Journal of clinical medicine · 2026Article
- Validation of Functional Lumen Imaging Probe Panometry Esophageal Motility Classification Version 2.0: A Study of 805 Patients.Neurogastroenterology and motility · 2025Article
- A combined endoscopy and functional lumen imaging probe panometry approach can expedite diagnosis of esophageal motility disorders.Gastrointestinal endoscopy · 2025Article
- Diagnostic Accuracy of Timed Barium Esophagram for Achalasia.Gastroenterology · 2025Article
- Functional Lumen Imaging Probe Panometry.Gastrointestinal endoscopy clinics of North America · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND &
aimsFunctional lumen imaging probe (FLIP) panometry evaluates esophageal motility at the time of sedated endoscopy and often parallels high-resolution manometry (HRM) performed in awake patients. This study aimed to assess the impact of endoscopic sedation on FLIP evaluation of esophageal motility.
methodsAdult patients who completed FLIP panometry during sedated endoscopy and had a conclusive Chicago Classification version 4.0 diagnosis on HRM were included in this retrospective study. HRM diagnoses relative to FLIP panometry motility classifications were compared by sedation type used during FLIP (ie, conscious sedation [CS] with midazolam and fentanyl or monitored anesthesia care [MAC] with propofol).
resultsA total of 454 patients (mean [standard deviation] age 53 [17] years; 62% female) completed FLIP panometry under CS (n = 174; 38%) or MAC (n = 280; 62%; 177/280 MAC included fentanyl). On comparison of CS versus MAC, HRM diagnoses within FLIP panometry motility classifications did not differ (P = .306 across all 5 FLIP panometry classifications; P values .202-.856 within specific FLIP classifications). The proportion of HRM diagnoses within each FLIP panometry classification also did not differ between FLIP completed with CS versus MAC with fentanyl (P = .098) or MAC without fentanyl (P = .0261).
conclusionsWhether CS or MAC was used as sedation during FLIP did not have a clinically significant impact on the relationship between diagnosis on FLIP panometry and HRM. This supports the validity of diagnosing esophageal motility disorders using FLIP panometry during sedated endoscopy.
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