Evidence map›Paper›PMID 39509510›Full record

ArticleScience (New York, N.Y.)2024

COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses.

Zhiyuan Chen, Joseph L-H Tsui, Bernardo Gutierrez, Simon Busch Moreno, Louis du Plessis, Xiaowei Deng, Jun Cai, Sumali Bajaj, Marc A Suchard, Oliver G Pybus and 3 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Substitutions affecting the HA-NA-receptor balance preceded the emergence of the pandemic 2009 H1N1 virus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zhiyuan ChenSchool of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.ORCID 0000-0001-6753-5606
Joseph L-H TsuiDepartment of Biology, University of Oxford, Oxford, UK.ORCID 0000-0001-7871-8627
Bernardo GutierrezDepartment of Biology, University of Oxford, Oxford, UK.ORCID 0000-0002-9220-2739
Simon Busch MorenoDepartment of Biology, University of Oxford, Oxford, UK.
Louis du PlessisDepartment of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland.ORCID 0000-0003-0352-6289
Xiaowei DengSchool of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.ORCID 0000-0002-9892-2470
Jun CaiSchool of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.ORCID 0000-0001-9495-1226
Sumali BajajDepartment of Biology, University of Oxford, Oxford, UK.ORCID 0000-0002-8313-819X
Marc A SuchardDepartments of Biostatistics, Biomathematics, and Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-9818-479X
Oliver G Pybus *Department of Biology, University of Oxford, Oxford, UK.ORCID 0000-0002-8797-2667
Philippe Lemey *Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.ORCID 0000-0003-2826-5353
Moritz U G Kraemer *Department of Biology, University of Oxford, Oxford, UK.ORCID 0000-0001-8838-7147
Hongjie Yu *School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, China.ORCID 0000-0002-6335-5648

Funding

Statistical Innovation to Integrate Sequences and Phenotypes for Scalable Phylodynamic InferenceR01AI153044 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Marc A. Suchard · 2021 to 2026
$2.4M
NIAID NIH HHS R01 AI153044Wellcome Trust
6 · The paper itself

Abstract

The global dynamics of seasonal influenza viruses inform the design of surveillance, intervention, and vaccination strategies. The COVID-19 pandemic provided a singular opportunity to evaluate how influenza circulation worldwide was perturbed by human behavioral changes. We combine molecular, epidemiological, and international travel data and find that the pandemic's onset led to a shift in the intensity and structure of international influenza lineage movement. During the pandemic, South Asia played an important role as a phylogenetic trunk location of influenza A viruses, whereas West Asia maintained the circulation of influenza B/Victoria. We explore drivers of influenza lineage dynamics across the pandemic period and reasons for the possible extinction of the B/Yamagata lineage. After a period of 3 years, the intensity of among-region influenza lineage movements returned to pre-pandemic levels, with the exception of B/Yamagata, after the recovery of global air traffic, highlighting the robustness of global lineage dispersal patterns to substantial perturbation.

Indexed as

COVID-19Influenza B virusInfluenza, HumanSeasonsAsiaHumansInfluenza A virusPandemicsPhylogenySARS-CoV-2Travel

Identifiers

PMID39509510
PMCPMC11760156

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.