Evidence map›Paper›PMID 39509384›Full record

ArticlePLOS digital health2024

Early identification of children with Attention-Deficit/Hyperactivity Disorder (ADHD).

Yang S Liu, Fernanda Talarico, Dan Metes, Yipeng Song, Mengzhe Wang, Lawrence Kiyang, Dori Wearmouth, Shelly Vik, Yifeng Wei, Yanbo Zhang and 8 more

Abstract read
In one paragraph

Article in PLOS digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yang S LiuDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0003-0406-8056
Fernanda TalaricoDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0001-6114-4233
Dan MetesMinistry of Health, Government of Alberta, Edmonton, Alberta, Canada.
Yipeng SongDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Mengzhe WangMinistry of Health, Government of Alberta, Edmonton, Alberta, Canada.
Lawrence KiyangMinistry of Health, Government of Alberta, Edmonton, Alberta, Canada.
Dori WearmouthMinistry of Health, Government of Alberta, Edmonton, Alberta, Canada.
Shelly VikAlberta Health Services, Edmonton, Alberta, Canada.
Yifeng WeiDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Yanbo ZhangDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Jake HaywardDepartment of Emergency Medicine, Faculty of Medicine and Dentistry, University of Alberta, Canada.
Ghalib AhmedDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Ashley GaskinOfford Centre for Child Studies, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.
Russell GreinerDepartment of Computing Science, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0001-8327-934X
Andrew GreenshawDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Alex AlexanderMinistry of Health, Government of Alberta, Edmonton, Alberta, Canada.
Magdalena JanusOfford Centre for Child Studies, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.
Bo CaoDepartment of Psychiatry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0001-9338-3271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signs and symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) are present at preschool ages and often not identified for early intervention. We aimed to use machine learning to detect ADHD early among kindergarten-aged children using population-level administrative health data and a childhood developmental vulnerability surveillance tool: Early Development Instrument (EDI). The study cohort consists of 23,494 children born in Alberta, Canada, who attended kindergarten in 2016 without a diagnosis of ADHD. In a four-year follow-up period, 1,680 children were later identified with ADHD using case definition. We trained and tested machine learning models to predict ADHD prospectively. The best-performing model using administrative and EDI data could reliably predict ADHD and achieved an Area Under the Curve (AUC) of 0.811 during cross-validation. Key predictive factors included EDI subdomain scores, sex, and socioeconomic status. Our findings suggest that machine learning algorithms that use population-level surveillance data could be a valuable tool for early identification of ADHD.

Identifiers

PMID39509384
PMCPMC11542831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.