Evidence map›Paper›PMID 39509038›Full record

ArticlePurinergic signalling2025

Electroacupuncture may alleviate inflammatory pain by downregulating the expression of P2Y

Shuai Hou, Cui-Yuan Chen, Rui-Zhu Zhou, Liu-Xuan He, Xiao-Xiao Zhao, Sha-Sha Chen, Sha Yang, Hai-Yan Yin, Shu-Guang Yu

Abstract read
In one paragraph

Article in Purinergic signalling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuai Hou *School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Cui-Yuan Chen *School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Rui-Zhu ZhouSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Liu-Xuan HeSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Xiao-Xiao ZhaoSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Sha-Sha ChenSchool of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Sha YangSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Hai-Yan YinSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. yinhaiyan@cdutcm.edu.cn.
Shu-Guang YuSchool of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. ysg@cdutcm.edu.cn.

Funding

National Natural Science Foundation of China 82230127Natural Science Foundation of Sichuan Province 2023NSFSC1826
6 · The paper itself

Abstract

Increasing evidence indicated that purinergic signalling involved in electroacupuncture (EA)-induced analgesia. Whether purinergic P2Y

Indexed as

ElectroacupunctureInflammationPainPain ManagementReceptors, Purinergic P2Somatosensory CortexAnimalsDown-RegulationMaleMiceMice, Inbred C57BLReceptors, Purinergic P2YP2ry14 protein, mouseReceptors, Purinergic P2Receptors, Purinergic P2YElectroacupuncture analgesiaInflammatory painP2RY14Primary somatosensory cortex of hindlimb

Identifiers

PMID39509038
PMCPMC12454244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.