Evidence map›Paper›PMID 39508888›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2024

Prospective randomized evaluation of transcutaneous carbon dioxide monitoring during complex electrophysiological procedures under deep sedation: the TRACES trial.

Yannick Teumer, Alexandra Buss, Federica Diofano, Deniz Aktolga, Lyuboslav Katov, Carlo Bothner, Tillman Dahme, Wolfgang Öchsner, Benjamin Mayer, Wolfgang Rottbauer and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04038476 (Prospective, Randomised Evaluation of Transcutaneous Carbon-dioxide Monitoring in Complex Electrophysiological Procedures in Deep Sedation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04038476 naunknown statusnot on this map

Prospective, Randomised Evaluation of Transcutaneous Carbon-dioxide Monitoring in Complex Electrophysiological Procedures in Deep Sedation

TypeinterventionalSponsorUniversity of UlmRan2019 to 2024Enrolled726ConditionsConscious Sedation During Procedure, Ablation of ArrhythmiasArmsStandard monitoring + transcutaneous CO2 monitoring, Standard monitoring
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yannick TeumerUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Alexandra BussUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Federica DiofanoUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Deniz AktolgaUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Lyuboslav KatovUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Carlo BothnerUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Tillman DahmeUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Wolfgang ÖchsnerDepartment of Anesthesiology and Intensive Care Medicine, Ulm University Medical Center, Albert-Einstein-Allee 23, Ulm, Germany.
Benjamin MayerInstitute for Epidemiology and Medical Biometry, Ulm University, Schwabstraße 13, 89075, Ulm, Germany.
Wolfgang RottbauerUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany.
Karolina Weinmann-EmhardtUlm University Heart Center, Albert-Einstein-Allee 23, Ulm, Germany. Karolina.weinmann-emhardt@uniklinik-ulm.de.ORCID http://orcid.org/0000-0002-5777-2998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe field of interventional electrophysiology is rapidly growing. For safe and efficient procedures sedation is needed for patient comfort and immobility. However, sedative and analgesic agents can induce respiratory depression, risking hypercapnia, hypoxia, and hypotension. This study evaluates the impact of adding transcutaneous carbon-dioxide (CO

methodsThis prospective, randomized study at Ulm University Heart Center included 726 patients undergoing treatment under deep sedation between August 2019 and October 2023. Patients were randomly assigned to standard monitoring or standard monitoring with continuous transcutaneous CO

resultsThe TCM-group included 357 patients, and the standard group had 348. The primary composite endpoint was reached by 195 patients (54.8%) in the TCM-group and 195 patients (56.5%) in the standard group (p = 0.642). However, peripheral venous CO

conclusionWhile transcutaneous CO CLINICAL

trial registrationClinicalTrials.gov, NCT04038476, 29 July 2019.

Indexed as

CO2Deep sedationElectrophysiologyHemodynamic outcomesRespiratory complicationsTranscutaneous carbon dioxide monitoring

Identifiers

PMID39508888

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.