Evidence map›Paper›PMID 39508848›Full record

ArticlePediatric surgery international2024

Assessment of transfer-time and time-to-surgery as risk factors to survival in Gastroschisis (GS) in a LMIC; an eight-year review.

Alaa Obeida, Rawan El-Hussein, Hadeer Mohamed NasrEldin, Mohammad Allam, Khaled Bahaaeldin, Sherif Kaddah, Aly Shalaby

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Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alaa ObeidaDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt. alaa.obeida@kasralainy.edu.eg.
Rawan El-HusseinDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.
Hadeer Mohamed NasrEldinDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.
Mohammad AllamDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.
Khaled BahaaeldinDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.
Sherif KaddahDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.
Aly ShalabyDepartment of Paediatric Surgery, Kasr AlAiny Faculty of Medicine, Cairo University Specialized Paediatric Hospital, Cairo University, Ali Ibrahim Street, Mounira, Cairo, 11241, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of Gastroschisis in LMICs continues to be a challenge and is associated with very poor outcomes in contrast with HICs where survival rates near 100%. The purpose of this work is to provide an overview of survival over the past 8 years in a high-flow tertiary centre in Africa. It also investigates the effect of transfer-time and time-to-surgery on outcome.

methodsRetrospective case note review of all GS admissions. The variables assessed were gender, gestational age, weight, type of GS, transfer time, time to surgery and type of surgery. The primary outcome was survival.

resultsA total of 171 GS cases were identified: 148 simple, 23 complex. Seven died before surgery. The median age at surgical intervention was 8.5 h (range, 0-48). Closure options ranged from single-staged (primary fascial, skin, umbilical flap and sutureless closure) or a staged (silo) closure. Overall survival was 34.5%. Cases transferred under 8 h had a 46% survival. Surgery under 12 h of life had highest survival, 45%. Simple GS survived better than complex GS (40% vs 10%). Primary closure had a significantly better survival compared to staged closure (51% vs 18%).

conclusionsTransfer-time < 8 h plays a vital role in survival of GS cases. Surgical intervention within 12 h of birth showed a statistically significant improvement in outcome. Primary closure was associated with better survival rates. LEVEL OF EVIDENCE: Level III.

Indexed as

GastroschisisTime-to-TreatmentDeveloping CountriesFemaleHumansInfant, NewbornMalePatient TransferRetrospective StudiesRisk FactorsSurvival RateTime FactorsAbdominal wall defectsAfricaEgyptGastroschisisTransfer time

Identifiers

PMID39508848
PMCPMC11543767

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