Evidence map›Paper›PMID 39508763›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation of C─C and C─N bonds.

Guangzheng Wei, Borui Duan, Tai-Ping Zhou, Wenya Tian, Chenghai Sun, Zhi Lin, Zixin Deng, Binju Wang, Zhengyu Zhang, Xudong Qu

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guangzheng Wei *Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.ORCID 0000-0002-5967-3168
Borui Duan *Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.ORCID 0000-0002-1043-502X
Tai-Ping Zhou *State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
Wenya TianState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, and Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
Chenghai SunState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, and Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhi LinState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, and Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0009-0005-2240-449X
Zixin DengState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, and Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
Binju WangState Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.ORCID 0000-0002-3353-9411
Zhengyu ZhangKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Xudong QuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.ORCID 0000-0002-3301-8536

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2023M742299MOST | National Natural Science Foundation of China (NSFC) 22107069MOST | National Natural Science Foundation of China (NSFC) 222122305MOST | National Natural Science Foundation of China (NSFC) 22277075MOST | National Natural Science Foundation of China (NSFC) 22307076MOST | National Natural Science Foundation of China (NSFC) 22377074MOST | National Natural Science Foundation of China (NSFC) 32371303Program of Shanghai Academic/Technology Research Leader 22XD1421300STCSM | Natural Science Foundation of Shanghai Municipality (上海å¸'自ç"¶ç§'å¦åŸºé‡') 23ZR1432800
6 · The paper itself

Abstract

P450 peroxidase activities are valued for their ability to catalyze complex chemical transformations using economical H

Indexed as

Cytochrome P-450 Enzyme SystemAdenineCatalysisHydrogen PeroxideMolecular Dynamics SimulationOxidation-ReductionAdenineCytochrome P-450 Enzyme SystemHydrogen Peroxidebiosynthesiscytochrome P450natural productsnucleobaseperoxidase

Identifiers

PMID39508763
PMCPMC11573659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.