Evidence map›Paper›PMID 39508736›Full record

ArticleeLife2024

Dynamic readout of the Hh gradient in the

Rosalío Reyes, Arthur D Lander, Marcos Nahmad

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Position-dependent feedback drives scaling and robustness of morphogen gradients.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Morphogens in the evolution of size, shape and patterning.Development (Cambridge, England) · 2024
    Review
  3. Article
  4. The impact of cell size on morphogen gradient precision.Development (Cambridge, England) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rosalío ReyesDepartment of Physiology, Biophysics, and Neurosciences; Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav), Mexico City, Mexico.
Arthur D LanderDepartment of Developmental and Cell Biology and Center for Complex Biological Systems, University of California, Irvine, Irvine, United States.ORCID https://orcid.org/0000-0002-4380-5525
Marcos NahmadDepartment of Physiology, Biophysics, and Neurosciences; Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav), Mexico City, Mexico.ORCID https://orcid.org/0000-0001-6300-5608

Funding

Uncover Strategies Used By Biological SystemsP50GM076516 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI NIE, QING · 2007 to 2016
$25.1M
Centre for Research and Advanced Studies of the National Polytechnic Institute, Mexico Institutional SupportConsejo Nacional de Humanidades, Ciencias y Tecnologías Graduate FellowshipNIGMS NIH HHS P50 GM076516NIH HHS GM076516
6 · The paper itself

Abstract

Understanding the principles underlying the design of robust, yet flexible patterning systems is a key problem in developmental biology. In the

Indexed as

Body PatterningDrosophila ProteinsHedgehog ProteinsSignal TransductionWings, AnimalAnimalsDrosophilaDrosophila melanogasterGene Expression Regulation, DevelopmentalModels, Theoreticaldpp protein, DrosophilaDrosophila ProteinsHedgehog Proteinshh protein, Drosophilacomputational biologydevelopmental biologyD. melanogasterDrosophila wing discHedgehog signalingmorphogen gradientpatterningprecisionrobustnesssystems biology

Identifiers

PMID39508736
PMCPMC11651649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.