Evidence map›Paper›PMID 39508727›Full record

ArticleMicrobiology (Reading, England)2024

Study of excess manganese stress response highlights the central role of manganese exporter Mnx for holding manganese homeostasis in the cyanobacterium

Mara Reis, Sanja Zenker, Prisca Viehöver, Karsten Niehaus, Andrea Bräutigam, Marion Eisenhut

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mara ReisComputational Biology, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Sanja ZenkerComputational Biology, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Prisca ViehöverGenetics and Genomics of Plants, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Karsten NiehausProteome and Metabolome Research, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Andrea BräutigamComputational Biology, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.
Marion EisenhutComputational Biology, Center for Biotechnology (CeBiTec) and Faculty of Biology, Bielefeld University, Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular levels of the essential micronutrient manganese (Mn) need to be carefully balanced within narrow borders. In cyanobacteria, a sufficient Mn supply is critical for ensuring the function of the oxygen-evolving complex as the central part of the photosynthetic machinery. However, Mn accumulation is fatal for the cells. The reason for the observed cytotoxicity is unclear. To understand the causality behind Mn toxicity in cyanobacteria, we investigated the impact of excess Mn on physiology and global gene expression in the model organism

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialHomeostasisManganeseStress, PhysiologicalSynechocystisIronTranscriptomeBacterial ProteinsIronManganesecyanobacteriamanganeseregulationRNA-seqtoxicitytransporter

Identifiers

PMID39508727
PMCPMC11649195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.