Evidence map›Paper›PMID 39508647›Full record

ArticleGut microbes

Mei-Jou Chen, Chia-Hung Chou, Tsun-Hsien Hsiao, Tien-Yu Wu, Chi-Ying Li, Yi-Lung Chen, Kuang-Han Chao, Tzong-Huei Lee, Ronnie G Gicana, Chao-Jen Shih and 6 more

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Treatment of Actinomyces europaeus and Clostridium innocuum necrotizing fasciitis: Case report and literature review.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Gut Bacteria Encode Reductases that Biotransform Steroid Hormones.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mei-Jou ChenDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Chia-Hung ChouDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Tsun-Hsien HsiaoSchool of Medicine, National Tsing Hua University, Hsinchu, Taiwan.
Tien-Yu WuBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Chi-Ying LiBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Yi-Lung ChenDepartment of Microbiology, Soochow University, Taipei, Taiwan.
Kuang-Han ChaoDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Tzong-Huei LeeInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
Ronnie G GicanaBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Chao-Jen ShihBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.
Guo-Jie Brandon-MongBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Yi-Li LaiBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.
Po-Ting LiDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Yu-Lin TsengDepartment of Obstetrics and Gynecology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.
Po-Hsiang WangGraduate Institute of Environmental Engineering, National Central University, Taoyuan, Taiwan.
Yin-Ru ChiangBiodiversity Research Center, Academia Sinica, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

\Levels of progesterone, an endogenous female hormone, increase after ovulation; progesterone is crucial in the luteal phase to maintain successful pregnancy and prevent early miscarriage. Both endogenous and exogenous progesterone are recycled between the liver and gut; thus, the gut microbiota regulate host progesterone levels by inhibiting enterohepatic progesterone circulation. Our data indicated

Indexed as

ClostridiumGastrointestinal MicrobiomeMice, Inbred C57BLOvarian FollicleProgesteroneAdultAnimalsFemaleHumansMetronidazoleMiceMetronidazoleProgesteroneClostridium innocuumepipregnanolonegut microbiomeinfertilitylow progesterone bioavailabilitymouseneurosteroidoral progesterone supplementprogesterone

Identifiers

PMID39508647
PMCPMC11545266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.