Evidence map›Paper›PMID 39508247›Full record

ReviewElectrophoresis2025

A Comprehensive Review on Capillary Electrophoresis-Mass Spectrometry in Advancing Biomolecular Research.

Laura Pont, María Vergara-Barberán, Enrique Javier Carrasco-Correa

Abstract readReview
In one paragraph

Review in Electrophoresis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura PontDepartment of Chemical Engineering and Analytical Chemistry, Institute for Research on Nutrition and Food Safety (INSA·UB), University of Barcelona, Barcelona, Spain.
María Vergara-BarberánCLECEM Group, Department of Analytical Chemistry, University of Valencia, Valencia, Spain.
Enrique Javier Carrasco-CorreaCLECEM Group, Department of Analytical Chemistry, University of Valencia, Valencia, Spain.ORCID 0000-0002-5580-559X

Funding

Generalitat Valenciana CIGE/2023/069Ministerio de Ciencia e Innovación PID2021-125459OB-I00Ministerio de Ciencia e Innovación PID2021-127137OB-I00
6 · The paper itself

Abstract

This review provides an in-depth exploration of capillary electrophoresis-mass spectrometry (CE-MS) in biomolecular research from 2020 to 2024. CE-MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites, such as lipids, carbohydrates, or amines, among others. The review extends to various CE modes and interfaces for the CE-MS coupling, offering comprehensive insights into their applications within biomolecular research. Furthermore, it effectively summarizes the conditions employed in CE-MS while also addressing critical aspects such as sample preparation requirements. Despite its advantages, the review highlights a gap between discovery and practical implementation, underscoring the need for large-scale validation and method standardization to fully realize the potential of CE-MS in biomolecular research.

Indexed as

Mass SpectrometryAnimalsElectrophoresis, CapillaryHumansPeptidesProteinsPeptidesProteinsbiomarkercapillary electrophoresis–mass spectrometry (CE–MS)oligonucleotidespeptidesprotein

Identifiers

PMID39508247
PMCPMC12461452

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.