Evidence map›Paper›PMID 39508096›Full record

ArticleCirculation. Cardiovascular imaging2024

Prognostic Value of Coronary Flow Capacity by

Emilia Zampella, Roberta Assante, Adriana D'Antonio, Teresa Mannarino, Valeria Gaudieri, Carmela Nappi, Parthiban Arumugam, Mariarosaria Panico, Pietro Buongiorno, Mario Petretta and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0002-8787-731X
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0002-6791-1656
Teresa MannarinoDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0003-2585-5315
Valeria GaudieriDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0002-0560-2997
Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0001-9404-4677
Parthiban ArumugamDepartment of Nuclear Medicine, Central Manchester Foundation Trust, Manchester, United Kingdom (P.A.).
Mariarosaria PanicoInstitute of Biostructure and Bioimaging, National Research Council, Naples, Italy (M. Panico).
Pietro BuongiornoDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).
Mario PetrettaInstitute for Research and Healthcare SYNLAB SDN, Diagnostic Imaging, Naples, Italy (M. Petretta).ORCID 0000-0002-8001-4298
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0003-3431-7658
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy (E.Z., R.A., A.D., T.M., V.G., C.N., P.B., A.C., W.A.).ORCID 0000-0003-2187-4076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary flow capacity (CFC) is a measure that integrates hyperemic myocardial blood flow and myocardial flow reserve to quantify the pathophysiological impact of coronary artery disease on vasodilator capacity. We assessed the prognostic value of CFC derived from

methodsWe studied 1967 patients with suspected coronary artery disease and normal myocardial perfusion at the semiquantitative analysis of stress/rest cardiac

resultsDuring a mean time of 41±27 months, 49 events occurred (2.5% cumulative event rate, with an annualized event rate of 0.5% person-years). At multivariable Cox analysis, coronary artery calcium score categories and impaired CFC resulted as independent predictors of events (both

conclusionsIn patients with suspected coronary artery disease and normal myocardial perfusion, impaired CFC is associated with a higher risk of cardiac events. Evaluating CFC can help identify patients' candidates for additional therapies to prevent future events.

Indexed as

Coronary Artery DiseaseCoronary CirculationMyocardial Perfusion ImagingPositron Emission Tomography Computed TomographyPredictive Value of TestsRubidium RadioisotopesAgedCoronary AngiographyCoronary VesselsFemaleFractional Flow Reserve, MyocardialHumansMaleMiddle AgedPrognosisRadiopharmaceuticalsRadiopharmaceuticalsRubidium-82Rubidium Radioisotopescoronary artery diseaseheart ventriclesmyocardial perfusion imagingpositron emission tomographyprognosis

Identifiers

PMID39508096
PMCPMC11575911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.