Evidence map›Paper›PMID 39507873›Full record

ArticleThe Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians2024

The "Weight" for a New Agent Is Almost Over: A Commentary on the Novel Triagonist Retatrutide for Obesity.

Maryam Deravi, Chris Piszczatoski, Bradley Phillips, Jessica Huston, Angelina Vascimini

Abstract read
In one paragraph

Article in The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam DeraviDepartment of Pharmacy Education and Practice, College of Pharmacy, University of Florida, Gainesville, FL.
Chris PiszczatoskiAdvanced Practitioners, Family Medicine, University of Florida Health Physicians, Gainesville, FL.
Bradley PhillipsDepartment of Pharmacy Education and Practice, College of Pharmacy, University of Florida, Orlando, FL.ORCID https://orcid.org/0000-0002-2157-9037
Jessica HustonDepartment of Pharmacy Education and Practice, College of Pharmacy, University of Florida, Jacksonville, FL.ORCID https://orcid.org/0000-0002-0860-2108
Angelina VasciminiDepartment of Pharmacy Education and Practice, College of Pharmacy, University of Florida, Gainesville, FL.ORCID https://orcid.org/0000-0003-0638-1214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retatrutide, a hormone receptor agonist targeting glucagon, glucagon-like peptide 1, and glucose-dependent insulinotropic polypeptide, is being developed to treat obesity. A literature review from April 2019 to April 2024 included such terms as "retatrutide," "LY3437943," "overweight," and "obesity." Phase I proof-of-concept studies led to phase II trials showing up to 24% body weight reduction and nearly 20 cm waist circumference reduction. The most common adverse effects were gastrointestinal. Ongoing phase II and III studies aim to further evaluate the safety and efficacy of retatrutide as a novel triagonist for obesity treatment.

Indexed as

obesityretatrutideweight

Identifiers

PMID39507873
PMCPMC11536522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.