Background: Our study of nurses in Tehran was conducted in June of 2020, when the lockdown from the pandemic had been implemented. Nurses had been faced with how to effectively manage their own emotion responses during patientcare. Objectives: Our study aims to evaluate how psychological and social resources were jointly related to the use of emotional labor through surface acting and deep acting among nurses at public hospitals. Design: The study design was a single-wave, cross-sectional self-report questionnaire survey containing validated measures where the nurses reported on their work experiences during the pandemic. Settings: The participants came from five out of 50 public hospitals within Tehran Participants: Of the 250 nurses chosen by using multi-stage randomly sampling, 224 were retained after listwise deletion of missing data and outliers. Method: Through a survey questionnaire, participants responded to scale measures of psychological hardiness, social support, and emotional labor to investigate the joint impact of hardiness and social support on emotional labor. Their responses provided information on the (1) validity and reliability of all variables, and (2) the hypothesized structural relations, using Results: Challenge and control were related to social support; coworker sympathy and supervisory support were related to surface acting; coworker sympathy was related to deep acting. Under strong support, high hardiness was most negatively related to surface acting and positively related to deep acting. Conclusion: Through coworker and supervisory support, hardiness became an effective means for nurses to regulate their own emotions during interactions to enhance patientcare.