Evidence map›Paper›PMID 39507676›Full record

ArticleHealth science reports2024

Self-reported physical activity and gait in older adults without dementia: A longitudinal study.

Janina Krell-Roesch, Jeremy A Syrjanen, Tobias Moeller, Jelena Krafft, Bettina Barisch-Fritz, Walter K Kremers, Farwa Ali, David S Knopman, Ronald C Petersen, Thorsten Stein and 3 more

Abstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Janina Krell-RoeschInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.ORCID 0000-0003-4011-9842
Jeremy A SyrjanenDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Tobias MoellerInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.
Jelena KrafftInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.
Bettina Barisch-FritzInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.
Walter K KremersDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Farwa AliDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
David S KnopmanDepartment of Neurology Mayo Clinic Rochester Minnesota USA.
Ronald C PetersenDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.
Thorsten SteinInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.
Alexander WollInstitute of Sports and Sports Science Karlsruhe Institute of Technology Karlsruhe Germany.
Maria VassilakiDepartment of Quantitative Health Sciences Mayo Clinic Rochester Minnesota USA.ORCID 0000-0001-8328-136X
Yonas E GedaDepartment of Neurology and the Franke Barrow Global Neuroscience Education Center Barrow Neurological Institute Phoenix Arizona USA.

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI KEJAL KANTARCI · 2019 to 2026
$33.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
Pathways linking neuropsychiatric symptoms with Alzheimer's disease neuroimaging biomarkers and the outcome of incident Mild Cognitive Impairment/ DementiaR01AG057708 · NIA · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI GEDA, YONAS E · 2018 to 2022
$1.7M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR21AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2018 to 2019
$437k
NIA NIH HHS P30 AG062677NIA NIH HHS R01 AG057708NIA NIH HHS R21 AG058738NIA NIH HHS R33 AG058738NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

Background and Aims: Physical activity (PA) is associated with higher gait speed. We aimed to examine the associations between PA and change in spatial and temporal gait measures as well as fall risk in community-dwelling individuals free of dementia. Methods: Longitudinal study among 4173 individuals aged ≥50 years (mean age 71 years; 2078 males; median follow-up 4 years) enrolled in the Mayo Clinic Study of Aging. Self-reported late-life PA was used to calculate overall PA and moderate-vigorous PA (MVPA) scores. Gait was assessed using GAITRite® and Zeno™ systems. Incident falls information was based on diagnostic codes retrieved from medical records. We ran linear mixed effects models to examine associations between z-scored PA variables and longitudinal gait parameters, adjusted for age, sex, education, body mass index (BMI), medical comorbidities, and including interactions between PA and time since baseline. In secondary analyses, we calculated Cox Proportional hazard models with age as time scale predicting incident falls by PA, adjusting for sex, education, BMI, medical comorbidities, and falls history. Results: At baseline, higher PA was associated with higher velocity (overall PA: estimate 2.9935; MVPA: 2.2961; Conclusion: Late-life PA was associated with favorable gait outcomes and decreased risk of incident falls. Thus, late-life PA may help to maintain gait performance and decrease fall risk in old age.

Indexed as

fall riskgaitlongitudinalphysical activity

Identifiers

PMID39507676
PMCPMC11539020

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.