Evidence map›Paper›PMID 39507519›Full record

ArticleSouthern African journal of infectious diseases2024

Knowledge and perceptions of South African blood donors towards biobanking and stool donation.

Shantelle Claassen-Weitz, Elloise du Toit, Sugnet Gardner-Lubbe, Brian Kullin, Gregory Bellairs, Caroline Hilton, Anika Chicken, Kirsten Welp, Hannah Livingstone, Adrian Brink

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Southern African journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shantelle Claassen-WeitzDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-2175-3776
Elloise du ToitDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-3360-6135
Sugnet Gardner-LubbeDepartment of Statistics and Actuarial Sciences, Faculty of Economic and Management Sciences, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0003-2762-9944
Brian KullinDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-5460-1977
Gregory BellairsWestern Cape Blood Services, Cape Town, South Africa.ORCID https://orcid.org/0009-0009-4356-1231
Caroline HiltonWestern Cape Blood Services, Cape Town, South Africa.ORCID https://orcid.org/0009-0004-6531-4702
Anika ChickenDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0001-6166-6269
Kirsten WelpDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-0839-8597
Hannah LivingstoneDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0003-4804-7425
Adrian BrinkDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-5350-9690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The complexity of contexts and varied purposes for which biome donation are requested are unknown in South Africa. Objectives: The aim of this study was to provide strategic data towards actualisation of whether a stool donor bank may be established as a collaborative between Western Cape Blood Services (WCBS) and the University of Cape Town (UCT). Method: We designed a cross-sectional, questionnaire-based survey to determine willingness of WCBS blood donors to donate stool specimens for microbiome biobanking. The study was conducted between 01 June 2022 and 01 July 2022 at three WCBS donation centres in Cape Town, South Africa. Anonymous blood donors who met the inclusion criteria were enrolled. Anonymised demographic and interview data were analysed statistically. Results: Analysis of responses from 209/231 blood donors demonstrated in a logistic regression model that compensation ( Conclusion: The survey provides strategic data for the establishment of a stool bank and provided an understanding of the underlying determinants regarding becoming potential donors. Contribution: This is the first report on the perspectives of potential participants in donating samples towards a stool microbiome biobank in South Africa, a necessity for faecal microbiota transplantation (FMT).

Indexed as

blood donations clinicsClostridioides difficilefaecal microbiota transplantationhuman microbiotamicrobial dysbiosismicrobiome biobankstool donors

Identifiers

PMID39507519
PMCPMC11538471

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.