Evidence map›Paper›PMID 39507431›Full record

ArticleRadiology case reports2025

Acute necrotizing encephalopathy in an infant: A case report.

Elisamia Ngowi, Zeenat Juneja, Jacqueline Gabone, Maria Bulimba, Mohamedraza Ebrahim, Yaser Abdallah

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisamia NgowiDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.
Zeenat JunejaDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.
Jacqueline GaboneDepartment of Radiology, Aga Khan Hospital, Dar Es Salaam 2289, Tanzania.
Maria BulimbaDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.
Mohamedraza EbrahimDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.
Yaser AbdallahDepartment of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute necrotizing encephalopathy is a rare, severe neurological condition, characterized by symmetrical necrotic brain lesions affecting the thalamus, cerebral white matter, brain stem, and cerebellum. Diagnosis relies on characteristic clinical and radiological features. We describe a 10-month-old female infant presenting with multiple seizures following a brief febrile upper respiratory illness. MRI of the brain showed bilateral symmetrical abnormal signal intensities involving both thalami and caudate nucleus, consistent with ANE. Management of ANE is symptom-related but high-dose steroids and IVIG have been used. This case highlights the importance of recognizing ANE beyond its usual geographic distribution. Early recognition and prompt management help improve outcomes.

Indexed as

Acute necrotizing encephalopathyCase report

Identifiers

PMID39507431
PMCPMC11539092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.