Evidence map›Paper›PMID 39507068›Full record

ArticleJournal of public health in Africa2024

The association of smoking and alcohol in colorectal cancer in black patients - Case-control study.

Mpho K Kgomo, Ratidzo L Zingoni, Piet J Becker

Abstract read
In one paragraph

Article in Journal of public health in Africa, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mpho K KgomoDepartment of Gastroenterology Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID https://orcid.org/0000-0001-9068-5477
Ratidzo L ZingoniDepartment of Internal Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-3865-5593
Piet J BeckerDepartment of Biostatistics, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-9384-6472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Studies have focused on smoking and alcohol as risk factors for colorectal cancer (CRC). Caucasians and other populations have been studied worldwide, and both smoking and alcohol have been validated as causes of CRC. However, there are limited data on the black population; studies that have been performed in Africa have not specifically focused on these two risk factors but rather in combination with other risks. Aim: To determine how smoking and alcohol affect the incidence of CRC in the African black population. Setting: Steve Biko Academic Hospital's gastrointestinal clinic. Methods: Subjects used for the study included black African patients above 18 years who had undergone a colonoscopy for suspected CRC between 2016 and 2018. Cases used were confirmed CRC on histology; controls were negative on histology. A minimum of 68 cases and 136 controls were needed for this study according to sample calculation. Hundred and ten cases and 220 controls were obtained in the final analysis. Data were collected between June 2019 and March 2020. Results: Smoking (odds ratio [OR] = 1.795, Conclusion: Both smoking and a combination of alcohol and smoking are significant risk factors in the development of CRC in the black African population. Contribution: Smoking, as in most population groups, is a risk factor for CRC. The observed protective role of alcohol needs to be confirmed in larger studies representing the African population.

Indexed as

Africanalcohollarge bowelneoplasmtobacco

Identifiers

PMID39507068
PMCPMC11538488

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.