Evidence map›Paper›PMID 39507051›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2024

Pharmacological investigations of newly synthesized oxazolones and imidazolones as COX-2 inhibitors.

Iqra Saleem Naz Babari, Muhammad Islam, Hamid Saeed, Humaira Nadeem, Hassaan Anwer Rathore

Abstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Oxazole-Based Molecules: Recent Advances on Biological Activities.Current topics in medicinal chemistry · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iqra Saleem Naz BabariPunjab University College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Muhammad IslamPunjab University College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Hamid SaeedPunjab University College of Pharmacy, University of the Punjab, Lahore, Pakistan.
Humaira NadeemRiphah Institute of Pharmaceutical Sciences, Riphah University Islamabad, Pakistan.
Hassaan Anwer RathoreCollege of Pharmacy, QU Health, Qatar University, Doha 2713, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxazoles and Imidazoles are heterocyclic compounds with significant biological activities. The present study explores the pharmacological effects of some new oxazole and imidazole derivatives as potential COX-2 inhibitors. Docking studies of the compounds against targeted proteins COX-2 and TACE manifested good binding affinities for both the targets supporting their anti-inflammatory potential. Compounds (3F-A, 3F-B, N-A, N-B) were evaluated for

Indexed as

Carrageenan induced paw edemaCOX-2 inhibitorsELISAH& E stainingImidazolesOxazolePCRTissue antioxidant activity

Identifiers

PMID39507051
PMCPMC11539464

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.