Evidence map›Paper›PMID 39507030›Full record

ArticleTranslational lung cancer research2024

Triple-targeted therapy of dabrafenib, trametinib, and osimertinib for the treatment of the acquired

Cheng-Di Weng, Ke-Jun Liu, Shi Jin, Jun-Wei Su, Yi-Hui Yao, Cheng-Zhi Zhou, Yu-Fa Li, Ze-Xin Chen, Hua-Jun Chen, Yan-Ying Li and 2 more

Abstract read
In one paragraph

Article in Translational lung cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cheng-Di Weng *Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Ke-Jun Liu *Dongguan Institute of Clinical Cancer Research, Dongguan Key Laboratory of Precision Diagnosis and Treatment for Tumors, The Tenth Affiliated Hospital of Southern Medical University (Dongguan People's Hospital), Dongguan, China.
Shi Jin *National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Perking Union Medical College, Shenzhen, China.
Jun-Wei SuGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yi-Hui YaoDepartment of Oncology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
Cheng-Zhi ZhouDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease; Guangzhou Medical University, Guangzhou, China.
Yu-Fa LiDepartment of Pathology, Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Ze-Xin ChenGuangdong Research Center of Organoid Engineering and Technology, Guangzhou, China.
Hua-Jun ChenGuangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Yan-Ying LiDepartment of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu, China.
Ke-Jing TangDivision of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jin-Ji YangGuangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The B-Raf proto-oncogene, serine/threonine kinase ( Methods: A multi-center retrospective review of medical records was performed to analyze Results: Thirteen patients with Conclusions: EGFR/BRAF/MEK triple-targeted therapy is an effective and safe approach for treating

Indexed as

B-Raf proto-oncogeneepidermal growth factor receptor (EGFR)Non-small cell lung cancer (NSCLC)resistanceserine/threonine kinase V600E (BRAF V600E)treatment strategy

Identifiers

PMID39507030
PMCPMC11535828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.