ArticleBMC psychiatry2024
Differential association between childhood trauma subtypes and neurocognitive performance in adults with major depression.
Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Cognitive Specificity Enhancement Training (CoST) in depressed patients with a history of childhood maltreatment: a pilot study on the feasibility and efficacy of CoST for reducing rumination, cognitive avoidance, and depressive symptoms.European journal of psychotraumatology · 2025Trial
- Brain network centrality following stress in adults with major depressive disorder and childhood trauma.Neurobiology of stress · 2026Article
- Network analysis of childhood trauma and meaning in life in adolescents with and without depression.BMC psychology · 2026Article
- Impact of childhood trauma on depressive symptoms in bipolar adolescents: the mediating effect of sleep disturbance.BMC psychiatry · 2025Article
- Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach.Children (Basel, Switzerland) · 2025Article
- Major depressive disorders in children aged 5-14 years: a Global Burden of Disease analysis from the perspective of exercise psychology.Frontiers in public health · 2025Article
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Authors and funding
11 authors.
Funding
Abstract
backgroundNeurocognitive impairment is one of the prominent manifestations of major depressive disorder (MDD). Childhood trauma enhances vulnerability to developing MDD and contributes to neurocognitive dysfunctions. However, the distinct impacts of different types of childhood trauma on neurocognitive processes in MDD remain unclear.
methodsThis study comprised 186 individuals diagnosed with MDD and 268 healthy controls. Childhood trauma was evaluated using the 28-item Childhood Trauma Questionnaire-Short Form. Neurocognitive abilities, encompassing sustained attention, vigilance, visual memory, and executive functioning, were measured by the Cambridge Neuropsychological Testing Automated Battery.
resultsMultivariable linear regressions revealed that childhood trauma and MDD diagnosis were independently associated with neurocognitive impairment. Physical neglect was associated with impaired visual memory and working memory. MDD diagnosis is associated with working memory and planning. Interactive analysis revealed that physical/sexual abuse was associated with a high level of vigilance and that emotional neglect was linked with better performance on cognitive flexibility in MDD patients. Furthermore, childhood emotional abuse, physical abuse, and emotional neglect were revealed to be risk factors for developing early-onset, chronic depressive episodes.
conclusionThus, specific associations between various childhood traumas and cognitive development in depression are complex phenomena that need further study.
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