Evidence map›Paper›PMID 39506705›Full record

ArticleBMC public health2024

The societal burden associated with adolescent idiopathic scoliosis: a cross-sectional burden-of-disease study.

Thomáy-Claire Ayala Hoelen, Silvia M A A Evers, Jacobus J Arts, Paul C Willems, Ghislaine A P G van Mastrigt

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Psychosocial Burden of Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Synthesis of Patient and Caregiver Perspectives.Health expectations : an international journal of public participation in health care and health policy · 2026
    Pooled it
  2. Pooled it
  3. Global evolution of adolescent idiopathic scoliosis research (1990-2025): a bibliometric and visualization analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomáy-Claire Ayala HoelenDepartment of Orthopedic Surgery, CAPHRI Research School, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands. thomay.hoelen@mumc.nl.
Silvia M A A EversDepartment of Health Services Research, Faculty of Health, Medicine and Life Sciences, CAPHRI, Maastricht University, Maastricht, The Netherlands.
Jacobus J ArtsDepartment of Orthopedic Surgery, CAPHRI Research School, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
Paul C WillemsDepartment of Orthopedic Surgery, CAPHRI Research School, Maastricht University Medical Center (MUMC+), Maastricht, The Netherlands.
Ghislaine A P G van MastrigtDepartment of Health Services Research, Faculty of Health, Medicine and Life Sciences, CAPHRI, Maastricht University, Maastricht, The Netherlands.

Funding

Interreg VA Flanders - the Netherlands program 2021TC16RFCB041
6 · The paper itself

Abstract

backgroundIn the general population the prevalence of adolescent idiopathic scoliosis (AIS) is 2–3%. There is growing awareness of how AIS affects the quality of life of patients. However, the extent of the societal burden AIS poses remains poorly understood. Therefore, this study aimed to determine the societal burden of AIS.

methodsA cross-sectional burden of disease study was conducted using a bottom-up, prevalence-based approach. Patients with AIS or guardians of a child diagnosed with AIS residing in the Netherlands were eligible for inclusion. The survey was distributed between June - December 2022 and was completed once by each participant. Costs were assessed using the institute for Medical Technology Assessment - Medical Consumption and Productivity Cost Questionnaires. The health-related quality of life (HRQoL) was assessed using the EuroQol 5D-5L/EuroQol 5D Youth and the Scoliosis Research Society-22 revised questionnaires. Costs and HRQoL were identified, measured, and valued.

resultsParticipants (n = 229) were predominantly female (92%), on average 35 years old, and were employed (65%). The societal cost for a patient with AIS in the Netherlands was €12,275 per year. The largest costs were estimated for the healthcare and productivity losses. The mean utility score for adults was 0.7 (SD 0.20). Severe pain was experienced by 10% of the adult participants and 44% reported to experience moderate pain/discomfort. Statistically significant differences between different age groups were present for the sector costs and HRQoL.

conclusionsAIS negatively impacts societal costs and the HRQoL. Reducing the burden that is posed on the productivity sector by AIS and further improving the HRQoL for AIS patients is needed.

Indexed as

Adolescent idiopathic scoliosisBurden of diseaseCost of illnessDutch populationHealth-related quality of life

Identifiers

PMID39506705
PMCPMC11539827

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.