Evidence map›Paper›PMID 39506661›Full record

ArticleBMC psychiatry2024

Modified dialectical behavior therapy-informed transdiagnostic intervention for emotional disorders: protocol for a randomized controlled trial.

Shen-Ing Liu, Chih-Hung Chang, Chen-Ju Lin, Shu-Chin Chen, Hui-Chun Huang, Ying Lin, Yi-Hung Chang, Hsiao-Mei Yeh, I-Chieh Lin, Shu-I Wu

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05989451 (Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders in Two Medical Centers), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05989451 narecruitingnot on this map

Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders in Two Medical Centers: a Randomized Controlled Trial

TypeinterventionalSponsorMackay Memorial HospitalRan2023 to 2026Enrolled250ConditionsAnxiety Disorder, Depressive DisorderArmsDialectical behavior therapy (DBT)
3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Shen-Ing LiuDepartment of Medicine, Mackay Medical College, No.46, Sec. 3, Zhongzheng Rd., Sanzhi Dist., New Taipei City, 252005, Taiwan.
Chih-Hung ChangDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Chen-Ju LinDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Shu-Chin ChenSuicide Prevention Center, Mackay Memorial Hospital, Taipei, Taiwan.
Hui-Chun HuangDepartment of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.
Ying LinDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Yi-Hung ChangDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Hsiao-Mei YehDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
I-Chieh LinDepartment of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Shu-I WuDepartment of Medicine, Mackay Medical College, No.46, Sec. 3, Zhongzheng Rd., Sanzhi Dist., New Taipei City, 252005, Taiwan. t140@mmc.edu.tw.

Funding

Aiding Decision-Making and Trial Design using Multivariate Network Meta-AnalysisR21MH110110 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DESANTIS, STACIA · 2017 to 2018
$479k
Department of Medical Research, Mackay Memorial Hospital MMH-113-19, MMH-MM-11103, MMH-111-51, MMH-MM-11002, MMH-110-110, MMH-109112, MMH-10914Mackay Memorial Hospital grant number: MMH-113-20)National Science Council grant number: 112-2314-B-195-007-MY3NIMH NIH HHS R21 MH110110
6 · The paper itself

Abstract

backgroundAnxiety and depressive disorders, characterized by high incidence and functional impairments, are emotional disorders with shared etiological and maintenance mechanisms. Dialectical behavior therapy (DBT) is a promising approach for the transdiagnostic treatment of emotional disorders. Developing a brief DBT intervention can facilitate the adoption of evidence-based therapy.

methodsThis protocol is for a 3-year single-blinded, two-arm randomized controlled trial. Individuals with depressive or anxiety disorder will be randomly allocated to a modified DBT-informed transdiagnostic psychotherapy group or a treatment-as-usual group. The intervention group will receive DBT individual therapy for 15 weeks. Power analyses revealed that the cohort should include a minimum of 250 participants. Preintervention, postintervention, and follow-up (after 3 months) assessments will be conducted. Primary outcomes will be severities of depression and anxiety rated by blind assessors. Intent-to-treat and per-protocol analyses will be conducted using the hierarchical linear model. Effect sizes will be estimated using Cohen's d.

resultTo the best of our knowledge, the proposed study will be the first randomized controlled trial to evaluate the efficacy of a modified DBT intervention in managing transdiagnostic emotional disorders in Chinese individuals.

conclusionThis intervention is expected to improve clinical outcomes, daily functioning, and quality of life. The trial will enrich the empirical evidence for transdiagnostic interventions, facilitating the implementation of evidence-based therapy and reducing the high prevalence and challenges (e.g., disability) of emotional disorders in the Chinese population. TRIAL REGISTRATION NUMBER: NCT05989451.

Indexed as

Anxiety DisordersDialectical Behavior TherapyAdultDepressive DisorderFemaleHumansMaleMiddle AgedNon-Randomized Controlled Trials as TopicSingle-Blind MethodAnxietyChineseDepressive disorderDialectical behavior therapyEmotional disorderTransdiagnostic psychotherapy

Identifiers

PMID39506661
PMCPMC11539636

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.