ArticleJournal of neurology1986
Somatosensory evoked potentials in comatose patients: correlation with outcome and neuropathological findings.
Article in Journal of neurology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Value and mechanisms of EEG reactivity in the prognosis of patients with impaired consciousness: a systematic review.Critical care (London, England) · 2018Pooled it
- A Novel Approach to Screen for Somatosensory Evoked Potentials in Critical Care.Neurocritical care · 2024Article
- Neurophysiological assessment of brain dysfunction in critically ill patients: an update.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Review
- Real-Time Detection and Monitoring of Acute Brain Injury Utilizing Evoked Electroencephalographic Potentials.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2016Article
- The prognosis of medical coma.Journal of neurology, neurosurgery, and psychiatry · 2001Article
- The management of medical coma.Journal of neurology, neurosurgery, and psychiatry · 1993Review
- Motor and somatosensory evoked potentials in coma: analysis and relation to clinical status and outcome.Journal of neurology, neurosurgery, and psychiatry · 1992Article
- Defining prognosis in medical coma.Journal of neurology, neurosurgery, and psychiatry · 1991Article
- Spatial mapping of SEP in comatose patients: improved outcome prediction by combined parietal N20 and frontal N30 analysis.Brain topography · 1991Article
- Brain function in patients with cerebral fat embolism evaluated using somatosensory and brain-stem auditory evoked potentials.Journal of neurology · 1989Article
- Somatosensory evoked potentials aiding the diagnosis of brain death.Neurosurgical review · 1988Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subcortical and early cortical somatosensory evoked potentials (SEPs) were recorded in 63 comatose patients and classified into five salient SEP grades, which were defined as follows: grade 1, normal SEP; grade 2, SEPs with a clearly recognizable scalp component N20, normal central conduction time but clearly distorted wave N20-P25; grade 3, SEPs with a still recognizable N20 but delayed central conduction time and severely altered wave N20-P25; grade 4, SEPs with absence of N20 but with a more or less recognizable P15; grade 5, SEPs with absence of both N20 and P15. When these five patterns were compared with outcome, it was found that bilaterally normal SEPs or only unilaterally distorted SEPs were generally followed by good outcomes. Bilaterally altered SEPs (grade 2 or 3) were indicative of reduced chances of full recovery. The great majority of patients showing either grade 4 or 5 SEPs died within a few days after the recording session. In 31 patients, it was found post mortem that grade-2 SEPs reflected cortical brain damage, whereas grade-3 SEPs correlated well with subcortical lesions. In post-traumatic patients, this SEP pattern corresponded to diffuse subcortical shearing lesions. Patients with grade 4 or 5 SEPs were found to have severe brain oedema giving rise to transtentorial herniation, which was combined with secondary midbrain haemorrhage and tonsillar herniation in all patients with bilateral grade-5 SEPs.
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