Evidence map›Paper›PMID 39506302›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2024

High-Resolution Anorectal Manometry and Balloon Expulsion Test Outcomes in Functional Constipation: A Comparative Study.

Huihui Shi, Li Li, Ling Huang, Wenwen Xia, Maoling Zhu, Yan Zhao

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07705542 (Analysing the Impact of Balloon Inflated vs Balloon Deflated Push Manoeuvres in Chronically Constipated Patients During Biofeedback Therapy), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07705542 narecruitingnot on this mapstarted 2026, after this paper: background citation

Analysing the Impact of Balloon Inflated vs Balloon Deflated Push Manoeuvres in Chronically Constipated Patients During Biofeedback Therapy

TypeinterventionalSponsorHull University Teaching Hospitals NHS TrustRan2026 to 2026Enrolled10ConditionsConstipation, Chronic Constipation, Dyssynergia, AnismusArmsInflating anorectal catheter balloon to defecatory desired volume during push manoeuvres in biofeedback therapy., No intervention
3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Huihui ShiDepartment of Gastroenterology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.
Li LiDepartment of Gastroenterology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.
Ling HuangDepartment of Gastroenterology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.
Wenwen XiaDepartment of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Maoling ZhuDepartment of Gastroenterology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.
Yan ZhaoDepartment of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Functional constipation can occur in children and adults and consists of difficult or infrequent bowel movements, painful defecation, or the sensation of incomplete bowel movement, and it can be idiopathic. This study aimed to compare the findings from high-resolution anorectal manometry (HRAM) and the balloon expulsion test (BET) in 360 patients with functional constipation and 73 healthy volunteers. MATERIAL AND METHODS In total, 360 patients with functional constipation and 73 healthy volunteers underwent HRAM and BET in our hospital from January 2017 to December 2023. We collected the general data of all participants and surveyed the defecation symptoms of patients with functional constipation. RESULTS Our study showed no significant correlation between HRAM results and age in healthy volunteers, while men had a higher residual anal pressure (P=0.022), higher anal squeeze pressure (P=0.020), and lower rectoanal pressure gradient than women (P=0.017). Using logistic regression analysis, it was concluded that sex (OR=2.880, 95% CI [1.654,5.015], P=0.000) and sensation of incomplete evacuation (OR=1.892, 95% CI [1.023,3.500], P=0.042) affected the occurrence of dyssynergic defecation. The specificity of BET in diagnosing dyssynergic defecation was 81.89%, while that of HRAM was 52.78%. CONCLUSIONS This observation provides normal values for anorectal pressures by HRAM. HRAM and BET are effective methods for assessing functional constipation. Being male and having sensation of incomplete evacuation are risk factors for dyssynergic defecation. The specificity of BET for diagnosing dyssynergic defecation was higher than that of HRAM.

Indexed as

Anal CanalConstipationDefecationManometryRectumAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedPressure

Identifiers

PMID39506302
PMCPMC11555885

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Registered trials

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