Evidence map›Paper›PMID 39506255›Full record

Trial reportClinical implant dentistry and related research2025

Evaluation of Internal and External Hexagon Connections in Immediately Loaded Full-Arch Rehabilitations: A Multicenter Randomized Split-Mouth Controlled Trial With a 6-Year Follow-Up.

Francesco Bagnasco, Maria Menini, Paolo Pesce, Umberto Gibello, Massimo Carossa, Francesco Pera

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesco BagnascoDepartment of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry, University of Genoa, Genoa, Italy.
Maria MeniniDepartment of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry, University of Genoa, Genoa, Italy.
Paolo PesceDepartment of Surgical Sciences (DISC), Division of Prosthodontics and Implant Prosthodontics Dentistry, University of Genoa, Genoa, Italy.ORCID https://orcid.org/0000-0001-8726-4145
Umberto GibelloC.I.R. Dental School, Department of Surgical Sciences, University of Turin, Turin, Italy.
Massimo CarossaC.I.R. Dental School, Department of Surgical Sciences, University of Turin, Turin, Italy.ORCID https://orcid.org/0000-0001-9495-1832
Francesco PeraC.I.R. Dental School, Department of Surgical Sciences, University of Turin, Turin, Italy.

Funding

Sweden and Martina
6 · The paper itself

Abstract

backgroundFull-arch immediate loading rehabilitations are now a widely used rehabilitation method that guarantees predictable medium- and long-term results. Numerous factors can influence its success and stability in the medium and long term. Among these the implant-abutment connection seems to play an important role, however there is still little information on which is the most suitable in this type of treatment. PURPOSE: The aim of the present multicenter split-mouth controlled trial is to evaluate whether external hexagonal connections (EHC) and internal hexagonal connections (IHC) can influence success, bone resorption and peri-implant parameters in immediate-load full-arch rehabilitations. MATERIALS AND

methodsTwenty patients were rehabilitated with immediately loaded fixed full-arch rehabilitations. All the implants presented the same macro- and micro-topography but different implant-abutment connection. IHC were used in one randomly selected side of the jaw and EHC was used in the other side. Outcome measures were implant survival rate, peri-implant marginal bone loss (MBL), plaque index (PI), probing depth (PD), and bleeding on probing (BoP) evaluated at 3, 6, 12, 36, and 72-month post-loading. Technical and biological complications were recorded.

resultsIn 20 patients, 43 EHC and 40 IHC implants were placed. Between 32 and 72 months of follow-up two patients withdrew (died) and no implants were lost. The cumulative survival rate (CSR) was 97.44% for EHC implants and 97.22% for IHC implants. The MBL presented a resorption of 2 mm in the EHC group and 1.9 mm in the IHC group. No statistically significant differences were found between the two groups for any of the parameters at any time. No biological or technical complications were detected between the 36th and 72nd month of follow-up.

conclusionsAfter 72 months in function, both internal and external hexagon connections provided good clinical outcomes and were not associated with any significant difference in the clinical outcomes.

Indexed as

Dental Implant-Abutment DesignDental Prosthesis, Implant-SupportedImmediate Dental Implant LoadingAdultAgedAlveolar Bone LossFemaleFollow-Up StudiesHumansMaleMiddle AgedPeriodontal IndexTreatment Outcomedental implantsfull‐arch rehabilitationimmediate loadingimplant‐abutment connectionsplit‐mouth study

Identifiers

PMID39506255
PMCPMC11789837

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.