Evidence map›Paper›PMID 39506212›Full record

Trial reportClinical implant dentistry and related research2025

Metal-Free Custom-Made Zirconia Implants-A Prospective 5-Year Follow-Up Single-Arm Clinical Trial.

Jantien H W de Beus, Marco S Cune, Henny J A Meijer, Gerry M Raghoebar, Ulf Schepke

Abstract readClinical Trial
In one paragraph

Trial report in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jantien H W de BeusDepartment of Periodontology, University of Groningen, University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Groningen, Netherlands.ORCID https://orcid.org/0000-0002-2811-4427
Marco S CuneDepartment of Restorative Dentistry, University of Groningen, University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Groningen, Netherlands.ORCID https://orcid.org/0000-0003-1589-5751
Henny J A MeijerDepartment of Oral Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.ORCID https://orcid.org/0000-0003-1702-6031
Gerry M RaghoebarDepartment of Oral Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.ORCID https://orcid.org/0000-0003-3578-7141
Ulf SchepkeDepartment of Restorative Dentistry, University of Groningen, University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Groningen, Netherlands.ORCID https://orcid.org/0000-0002-5995-0735

Funding

University Medical Center GroningenZV3 (Germany), Manufacturer of Zirconium Implants (ZrO2)
6 · The paper itself

Abstract

backgroundDental implants made of zirconia (ZrO

aimThe aim of this study was to describe and to examine the clinical performance of custom-made two-piece ZrO MATERIAL AND

methodsOf the 31 included patients in this prospective 5-year follow-up single-arm clinical trial, 30 received a custom-made ZrO

resultsSurvival and success probabilities after 5 years were, respectively, 75.8% (95% CI [60.0%; 91.0%]) and 71.0% (95% CI [54.0%; 88.0%]) for the custom-made ZV3 implants. No significant differences in survival rate were found after stratification on "manipulation of the implant" and on "occlusal scheme." Mean bone-level alteration between baseline and the first follow-up was +0.06 mm (95% CI [-0.23 mm; 0.12 mm]; SD = 0.42 mm) and between baseline and the second follow-up was +0.04 mm (95% CI [-0.35 mm; 0.26 mm]; SD = 0.54 mm). Patients' satisfaction for patients with implants still in function after 5 years was 91.7% (IQR = [90.5%-97.3%]), indicating satisfaction with the treatment. Pooled satisfaction in patients with successful implants after 5 years was significantly higher than patients' expressed expectations before treatment. None of the crowns failed, and no interventions were required. CONCLUSION AND CLINICAL IMPLICATIONS: Survival rate of these particular ZV3 implants in our study was lower than expected and clinically not acceptable. Hence, ZV3 implant placement as applied in this study cannot be recommended for clinical practice. Further research on the different appearances of mechanical failure in ZrO

Indexed as

Dental ImplantsDental Implants, Single-ToothDental Prosthesis DesignZirconiumAdultAgedCrownsDental Prosthesis, Implant-SupportedDental Restoration FailureFemaleFollow-Up StudiesHumansMaleMaxillaMiddle AgedProspective StudiesDental ImplantsZirconiumzirconium oxidedental implantsmetal‐free dentistryzirconia

Identifiers

PMID39506212
PMCPMC11789843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.