Evidence map›Paper›PMID 39506107›Full record

ArticleNature2024

Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.

Maude Jans, Magdalena Kolata, Gillian Blancke, Aline D'Hondt, Claudia Gräf, Maarten Ciers, Mozes Sze, Alexandra Thiran, Ioanna Petta, Vanessa Andries and 10 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Gut microbiota in health and disease.Molecular biomedicine · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Deciphering the Implications ofPathogens (Basel, Switzerland) · 2026
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Maude Jans *VIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0003-2888-0671
Magdalena Kolata *Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-5918-3177
Gillian BlanckeVIB Center for Inflammation Research, Ghent, Belgium.
Aline D'HondtStructural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.ORCID 0000-0002-0257-9381
Claudia GräfStructural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.ORCID 0009-0000-9892-7143
Maarten CiersVIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0001-5995-6822
Mozes SzeVIB Center for Inflammation Research, Ghent, Belgium.
Alexandra ThiranVIB Center for Inflammation Research, Ghent, Belgium.
Ioanna PettaVIB Center for Inflammation Research, Ghent, Belgium.
Vanessa AndriesVIB Center for Inflammation Research, Ghent, Belgium.
Sara VerbandtDepartment of Oncology, Catholic University Leuven, Leuven, Belgium.
Engy ShokryCancer Research UK Scotland Institute, Glasgow, UK.
David SumptonCancer Research UK Scotland Institute, Glasgow, UK.ORCID 0000-0002-9004-4079
Johan Vande VoordeSchool of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow, UK.ORCID 0000-0002-7686-0926
Geert BerxDepartment of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Sabine TejparDepartment of Oncology, Catholic University Leuven, Leuven, Belgium.ORCID 0000-0003-3281-8643
Geert van LooVIB Center for Inflammation Research, Ghent, Belgium.ORCID 0000-0002-8427-4775
Iliyan D IlievJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0003-0884-9749
Han RemautStructural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-9775-4102
Lars VereeckeVIB Center for Inflammation Research, Ghent, Belgium. lars.vereecke@irc.vib-ugent.be.ORCID 0000-0002-1593-862X

Funding

Commensal fungal communities in the regulation of immunity and intestinal inflammation.R01DK113136 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIYAN Dimitrov ILIEV · 2017 to 2026
$4.2M
Mononuclear phagocyte networks in mycobiota regulation and antifungal immunity.R01DK121977 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIEV, ILIYAN DIMITROV · 2020 to 2024
$2.7M
The role of the mycobiome in cancerR01CA286920 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIYAN Dimitrov ILIEV · 2024 to 2026
$1.5M
NCI NIH HHS R01 CA286920NIDDK NIH HHS R01 DK113136NIDDK NIH HHS R01 DK121977
6 · The paper itself

Abstract

Various bacteria are suggested to contribute to colorectal cancer (CRC) development

Indexed as

Adhesins, Escherichia coliBacterial AdhesionColorectal NeoplasmsEpithelial CellsMutagensPeptidesPolyketidesAnimalsCell Line, TumorDisease Models, AnimalDNA DamageEscherichia coliFemaleFimbriae ProteinsHumansMaleAdhesins, Escherichia colicolibactinFimbriae ProteinsfimH protein, E coliMutagensPeptidesPolyketides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.