ArticleScientific reports2024
Comparative genomics of the highly halophilic Haloferacaceae.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Complete genome sequence of the carotenoid producing halophilic archaeonMicrobiology resource announcements · 2026Article
- Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026Review
- The pangenome: a statistical model, not a fixed biological property.Bioinformatics advances · 2026Review
- iHalo: a genome-based machine learning model using k-mer for halophiles identification.World journal of microbiology & biotechnology · 2025Article
- Genomic and Physiological Signatures of Evolution in ANAMMOX Bacteria.Environmental microbiology reports · 2025Review
- Genomic insights into phenol degradation by halophilic bacteria and their potential application in saline soil remediation.Scientific reports · 2025Article
- Global dominance of Haloquadratum walsbyi by a single genomovar with distinct gene content and viral cohorts from close relatives.The ISME journal · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Haloferacaceae are a family of extremely halophilic archaea with many species producing enzymes and products beneficial for industrial biotechnology. They are, however, relatively under-characterised with regards to genetics and gene products. This study aims to use existing sequence data to highlight genetic diversity, create pangenomes for three genera, and provide secondary metabolite and pathway analysis. This will establish current knowledge and identify key gaps in research. We show that the Haloferacaceae have significant genetic diversity between genera, with numerous gene gain and loss events in key genera. It also found that the model genus, Haloferax, has relatively low identified secondary metabolites compared to other genera within the family. Additionally, this study has identified potential biotechnology targets for heterologous expression in model organisms.
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Registered trials
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