Evidence map›Paper›PMID 39505960›Full record

ArticleScientific reports2024

Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridine.

Katarzyna Malarz, Patryk Ziola, Dawid Zych, Patryk Rurka, Anna Mrozek-Wilczkiewicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katarzyna MalarzDepartment of Systems Biology and Engineering, Silesian University of Technology, Akademicka 2A, Gliwice, 44-100, Poland.
Patryk ZiolaA. Chełkowski Institute of Physics, University of Silesia in Katowice, 75 Pułku Piechoty 1a, Chorzów, 41- 500, Poland.
Dawid ZychFaculty of Chemistry, University of Opole, Oleska 48, Opole, 45-052, Poland.
Patryk RurkaA. Chełkowski Institute of Physics, University of Silesia in Katowice, 75 Pułku Piechoty 1a, Chorzów, 41- 500, Poland.
Anna Mrozek-WilczkiewiczDepartment of Systems Biology and Engineering, Silesian University of Technology, Akademicka 2A, Gliwice, 44-100, Poland. anna.mrozek-wilczkiewicz@us.edu.pl.

Funding

Narodowe Centrum Nauki 2019/35/B/NZ5/04208Narodowe Centrum Nauki 2020/39/O/NZ5/02342
6 · The paper itself

Abstract

Compounds that can induce oxidative stress in cancer cells while remaining nontoxic to healthy cells are extremely promising for potential anticancer drugs. 2,2':6',2''-terpyridine-metal complexes possess these properties. The high level of activity (IC

Indexed as

Coordination ComplexesHomeostasisOxidation-ReductionPyridinesReactive Oxygen SpeciesSignal TransductionAntineoplastic AgentsApoptosisAutophagyCell Line, TumorHumansOxidative StressAntineoplastic AgentsCoordination ComplexesPyridinesReactive Oxygen Species2,2′:6′,2′′-terpyridineAnticancer activityApoptosisAutophagyCell cycle inhibitionOxidative stressReactive oxygen species

Identifiers

PMID39505960
PMCPMC11541782

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.