Evidence map›Paper›PMID 39505777›Full record

Trial reportClinical oral investigations2024

Impact of platelet-rich fibrin derivatives on patient morbidity and quality of life in palatal donor sites following free gingival graft surgery: a randomized clinical trial.

Dilek Özkan Şen, Betül Irız Şengül, Fatma Uçan Yarkaç, Elif Öncü

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07258472 (Multidimensional Assessment of Preoperative Anxiety and Quality of Life on Postoperative Patient-Reported Outcomes Following Free Gingival Graft Surgery), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07258472 nacompletednot on this map

Multidimensional Assessment of Preoperative Anxiety and Quality of Life on Postoperative Patient-Reported Outcomes Following Free Gingival Graft Surgery

TypeinterventionalSponsorIstanbul Gelisim UniversityRan2016 to 2017Enrolled36ConditionsGingival Recession, Dental Anxiety, Quality of LifeArmsFree Gingival Graft (FGG) Surgery
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dilek Özkan ŞenDepartment of Periodontology, Faculty of Dentistry, Necmettin Erbakan University, Konya, 42050, Turkey. dilekozkan19@hotmail.com.ORCID 0000-0002-0531-1217
Betül Irız ŞengülDepartment of Periodontology, Faculty of Dentistry, Necmettin Erbakan University, Konya, 42050, Turkey.ORCID 0000-0002-7088-6762
Fatma Uçan YarkaçDepartment of Periodontology, Faculty of Dentistry, Necmettin Erbakan University, Konya, 42050, Turkey.ORCID 0000-0001-8126-585X
Elif ÖncüDepartment of Periodontology, Faculty of Dentistry, Panorama Dental Clinic, Lokman Hekim University, Ankara, Turkey.ORCID 0000-0002-5774-4604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPlatelet concentrates are biomaterials with significant potential in tissue regeneration, functioning as scaffolds with greater leukocyte inclusion and a flexible fibrin mesh. However these concentrates have different preparation methods and biological properties. The objective of this clinical investigation was to evaluate the effects of utilizing platelet-rich fibrin (PRF) materials (L-PRF and A-PRF) as a palatal bandage following free gingival graft (FGG) on patients' morbidity and oral health-related quality of life. MATERIALS AND

methodsThirty-nine participants received FGG to promote keratinized tissue and treat gingival recession. Participants were randomly assigned to L-PRF, A-PRF, and control groups, with 13 participants in each. They used a visual analog scale (VAS) to rate their pain, analgesic medication use, dietary changes, discomfort, and bleeding at 1-7 days, 14 days and 1 month during the healing process. Patients' quality of life was assessed using the Oral Health Impact Profile (OHIP-14) at baseline, 1-7 days, 14 days, 1 month, and 6 months.

resultsThere was no difference in anxiety levels between the all groups. (p > 0.05). The control group had higher OHIP-14 total scores than the other groups, but the differences were not statistically significant, especially in the first seven days (p > 0.05). In addition, the PRF groups showed an improvement in quality of life after 14 days, 1 month, and 6 months (p < 0.05). Patients' pain and suffering decreased with healing. The control group took more postoperative analgesics than PRF groups. In addition, there was a significant decrease in patient complaints about medicine intake, bleeding, pain, perceived sensitivity, and dietary modifications in all groups during follow-up.

conclusionsPRF palatal bandages may improve patient's quality of life, donor site healing, postoperative pain and morbidity. CLINICAL RELEVANCE: This study found that preserving the palate in FGG and employing PRF materials that speed palate healing reduce discomfort and morbidity.

Indexed as

Gingival RecessionPain MeasurementPlatelet-Rich FibrinQuality of LifeAdultFemaleGingivaHumansMaleMiddle AgedPalatePostoperative PainTransplant Donor SiteTreatment OutcomeWound HealingAnxietyFree gingival graftPlatelet-rich fibrinQuality of lifeVAS

Identifiers

PMID39505777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.