Evidence map›Paper›PMID 39505762›Full record

ArticleAnnals of biomedical engineering2025

The Effect of Low-Dose CT Protocols on Shoulder Model-Based Tracking accuracy Using Biplane Videoradiography.

Stacey Chen, Erin C S Lee, Kelby B Napier, Michael J Rainbow, Rebekah L Lawrence

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Article in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Stacey ChenProgram in Physical Therapy, Washington University School of Medicine in St. Louis, 4444 Forest Park Avenue, St. Louis, MO, 63108, USA.ORCID http://orcid.org/0000-0001-6365-8748
Erin C S LeeDepartment of Mechanical and Materials Engineering, Queen's University, McLaughlin Hall, 130 Stuart Street, Kingston, Ontario, Canada.ORCID http://orcid.org/0000-0002-2311-1454
Kelby B NapierMallinckrodt Institute of Radiology, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, St Louis, MO, 63110, USA.ORCID http://orcid.org/0000-0003-3380-8412
Michael J RainbowDepartment of Mechanical and Materials Engineering, Queen's University, McLaughlin Hall, 130 Stuart Street, Kingston, Ontario, Canada.
Rebekah L LawrenceProgram in Physical Therapy, Washington University School of Medicine in St. Louis, 4444 Forest Park Avenue, St. Louis, MO, 63108, USA. r.lawrence@wustl.edu.ORCID http://orcid.org/0000-0003-3777-8169

Funding

PURCHASE OF A SIEMENS NEXT GENERATION PET/CTS10OD025214 · OD · WASHINGTON UNIVERSITY · PI WOODARD, PAMELA K · 2018 to 2018
$2.0M
Investigating the Multi-factorial Etiology of Rotator Cuff Pathology in Human SubjectsR00AR075876 · NIAMS · WASHINGTON UNIVERSITY · PI LAWRENCE, REBEKAH L · 2022 to 2025
$705k
NIAMS NIH HHS R00 AR075876NIAMS NIH HHS R00AR075876NIH HHS S10 OD025214
6 · The paper itself

Abstract

purposeModel-based tracking is being increasingly used to quantify shoulder kinematics and typically employs computed tomography (CT) to create the 3D bone volumes, which adds to the total radiation exposure. Lower-dose CT protocols may be possible given the contrast between bone and the surrounding soft tissues. The purpose of this study was to describe the dose-accuracy tradeoff between low-dose CT scans and the kinematic tracking accuracy of the humerus, scapula, and clavicle when tracked using an intensity-based registration algorithm.

methodsThree fresh-frozen cadavers consisting of the torso and bilateral shoulders were tested. The CT protocols investigated included a full-dose protocol and 4 experimental low-dose protocols that modulated x-ray tube current and peak voltage. Bead-based tracking (i.e., radiostereometric analysis) served as the reference standard to which model-based tracking results were compared. Accuracy was described in terms of both segmental (humerus, scapula, and clavicle) and joint (glenohumeral, acromioclavicular) kinematics using root-mean-square (RMSE), bias, precision, and worst-case errors.

resultsThe low-dose CT scans resulted in an average dose reduction of 70.6-92.8%. RMSEs tended to increase as CT dose decreased with average glenohumeral errors increasing from 0.5° and 0.6 mm to 0.6° and 0.6 mm between the highest and lowest-dose protocols, and average acromioclavicular errors increasing from 0.6° and 0.8 mm to 0.7° and 0.9 mm. However, the difference in joint kinematic errors between the highest and lowest-dose CT scanning protocols was generally small (≤0.3°, ≤ 0.1 mm).

conclusionIt is possible to substantially reduce the CT dose associated with shoulder motion analysis using biplane videoradiography without significantly impacting data fidelity.

Indexed as

Models, BiologicalShoulderShoulder JointTomography, X-Ray ComputedCadaverFemaleHumansHumerusMaleRadiation DosageAcromioclavicularBiplane videoradiographyGlenohumeralKinematicsModel-based tracking

Identifiers

PMID39505762
PMCPMC11805650

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.