Evidence map›Paper›PMID 39505758›Full record

SynthesisWorld journal of urology2024

The outcomes of robot-assisted surgery in the treatment of neurogenic lower urinary tract dysfunctions: a systematic review and meta-analysis.

Paolo Geretto, Sabrina De Cillis, Nadir I Osman, Fabiana Cancrini, Mehmet Gokhan Culha, Steeve Doizi, Cyrille Guillot-Tantay, Francois Herve, Mikolaj Przydacz, Nicholas Raison and 5 more

Abstract readMeta-AnalysisSystematic Review
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In one paragraph

Synthesis in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Paolo GerettoDivision of Neuro-Urology, Department of Surgical Sciences, Citta della Salute e della Scienza University Hospital, Via Gianfranco Zuretti 24, 10143, Turin, Italy. Paolo.gere@gmail.com.
Sabrina De CillisDivision of Urology, Department of Oncology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.
Nadir I OsmanDepartment of Urology, Royal Hallamshire Hospital, Sheffield, UK.
Fabiana CancriniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University, Rome, Italy.
Mehmet Gokhan CulhaDepartment of Urology, Prof. Dr. Cemil Tascioglu City Hospital, University of Health Sciences, Istanbul, Turkey.
Steeve DoiziDepartment of Urology, Sorbonne University, Assistance Publique-Hôpitaux de Paris, Tenon Academic Hospital, Paris, France.
Cyrille Guillot-TantayService d'urologie, Hôpital Foch, Suresnes, France.
Francois HerveDepartment of Urology, ERN Accredited Centrum, Ghent University Hospital, Ghent, Belgium.
Mikolaj PrzydaczDepartment of Urology, Jagiellonian University Medical College, Krakow, Poland.
Nicholas RaisonDepartment of Urology, King's College Hospital, King's College London, London, UK.
Antonio Tienza FernandezDepartment of Urology, Son Espases University Hospital, Health Research Institute of the Balearic Islands, Palma, Spain.
Manuela TutoloUnit of Urology, Division of Oncology, Urological Research Institute, IRCCS San Raffaele Hospital, Milan, Italy.
Luis ValeDepartment of Urology, Centro Hospitalar Universitario Sao Joao, Porto, Portugal.
Véronique PhéDepartment of Urology, Sorbonne University, Assistance Publique-Hôpitaux de Paris, Tenon Academic Hospital, Paris, France.
EAU-YAU Functional Urology Working group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the outcomes of robotic surgery for patients with neurogenic lower urinary tract dysfunctions (NLUTD). MATERIALS AND

methodsStudies evaluating the outcomes (efficacy and safety) of robot-assisted ileal conduit creation or artificial urinary sphincter (R-AUS) implantation or augmentation cystoplasty or continent urinary diversion creation in patients with NLUTD were included. The search strategy and studies selection were performed on Medline, Embase and Cochrane using the PICOS method according to the PRISMA statement (PROSPERO 2022 CRD42022333157). The comparator, if available, was the use of open or laparoscopic technique. Meta-analysis was performed whenever possible. The remaining articles were synthesized narratively.

resultsEight articles were included. Five described the outcomes of robot-assisted cystectomy with ileal conduit creation, two described the outcomes of augmentation cystoplasty and continent urinary diversion creation and one described R-AUS implantation in patients with NLUTD. The risk of bias was high. Three articles comparing the outcomes of robotic and open cystectomy and ileal conduit creation were suitable for meta-analysis. According to our meta-analysis, robot-assisted surgery had better outcomes compared to open surgery in terms of high-grade early postoperative complications (OR 0.39; 0.19-0.79; p = 0.01), days to bowel recovery (Cohen's D = - 0.62  ± 0.14, p < 0.001), length of hospitalisation (Cohen's D = - 0.28 ± 0.13; p = 0.03) and estimated blood loss (Cohen's D = - 1.17 ± 0.14, p < 0.001).Regarding AUS implantation, augmentation cystoplasty and continent urinary diversion creation, the outcomes from the articles included in our systematic review showed a 16-40% overall early complication rate in case of augmentation cystoplasty and 22% in case of AUS implantation.

conclusionsRobot-assisted surgery may have several advantages over open surgery in the treatment of NLUTDs. However, current evidence is insufficient to draw firm conclusions. Further high-quality studies are needed to better understand the role of robotic surgery in the treatment of NLUTD.

Indexed as

Robotic Surgical ProceduresUrinary Bladder, NeurogenicCystectomyHumansLower Urinary Tract SymptomsTreatment OutcomeUrinary DiversionArtificial urinary sphicterAugmentation cystoplastyContinent urinary diversionIleal conduitNeurogenic bladderNLUTDRobotic surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.