Evidence map›Paper›PMID 39505523›Full record

ArticleNeurologia medico-chirurgica2024

Usefulness of Mechanical Thrombectomy in Patients with Cancer Who Developed Cerebral Infarction.

Sayaka Terazono, Yuki Sakaeyama, Yutaka Fuchinoue, Masataka Mikai, Shuhei Kubota, Mitsuyoshi Abe, Kosuke Kondo, Nobuo Sugo, Takaaki Nagao, Masaaki Nemoto

Abstract read
In one paragraph

Article in Neurologia medico-chirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sayaka TerazonoDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Yuki SakaeyamaDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Yutaka FuchinoueDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Masataka MikaiDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Shuhei KubotaDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Mitsuyoshi AbeDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Kosuke KondoDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Nobuo SugoDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University.
Takaaki NagaoDepartment of Neurosurgery (Sakura), Faculty of Medicine, Toho University.
Masaaki NemotoDepartment of Neurosurgery (Sakura), Faculty of Medicine, Toho University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical thrombectomy (MT) is an established treatment for large vessel occlusion in the acute phase of stroke. However, its efficacy and safety in patients with cancer remain unclear. This study aimed to evaluate the therapeutic effect of MT against large vessel occlusion between patients with and without cancer. A total of 71 patients who underwent MT from August 2014 to November 2021 were included in this study. Patients with cancer and/or a history of cancer (n = 16) were included in the with cancer group and the remaining patients in the without cancer group (n = 55). The frequency of preoperative tissue plasminogen activator administration was significantly lower in the with cancer group (n = 2 [12.5%]) than in the without cancer group (n = 24 [43.6%]). However, there were no significant differences between the two groups in terms of treatment time, pass frequency, thrombolysis in cerebral infarction grade, modified Rankin scale score at 1 week after treatment [mRS (1w) ], modified Rankin scale score at discharge [mRS (ENT) ], modified Rankin scale score at 90 days after treatment [mRS (90 days) ], and length of hospital stay (days). In the multivariate analysis, if the objective variables were mRS (1w) and mRS (90 days), the National Institutes of Health Stroke Scale (NIHSS) and preonset mRS scores were considered significant variables. The presence or absence of cancer was not considered an independent factor of mRS (1w), mRS (ENT), or mRS (90 days). Aggressive treatment may be recommended to patients with cancer and/or a history of cancer who present with a systemic condition that can be managed with MT.

Indexed as

Cerebral InfarctionNeoplasmsThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTissue Plasminogen ActivatorTreatment OutcomeTissue Plasminogen Activatorcancercarcinomamechanical thrombectomyTrousseau syndrome

Identifiers

PMID39505523
PMCPMC11729256

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.