Evidence map›Paper›PMID 39505512›Full record

ReviewInvestigative and clinical urology2024

Prostate cancer theragnostics biomarkers: An update.

Sathish Kumar Am, Prabhakar Rajan, Mohammad Alkhamees, Merrel Holley, Vinoth-Kumar Lakshmanan

Abstract readReview
In one paragraph

Review in Investigative and clinical urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sathish Kumar AmProstate Cancer Biomarker Laboratory, Faculty of Clinical Research, Sri Ramachandra Institute of Higher Education & Research, Chennai, India.ORCID 0009-0009-3474-7536
Prabhakar RajanCentre for Cancer Cell and Molecular Biology, Barts Cancer Institute, Cancer Research UK City of London Centre, London, UK.ORCID 0000-0001-8064-9878
Mohammad AlkhameesDepartment of Urology, College of Medicine, Majmaah University, Al Majmaah, Saudi Arabia.ORCID 0000-0001-8207-1870
Merrel HolleyInternational Hyperbaric Medical Foundation, Morgan City, LA, USA.ORCID 0000-0003-4678-080X
Vinoth-Kumar LakshmananProstate Cancer Biomarker Laboratory, Faculty of Clinical Research, Sri Ramachandra Institute of Higher Education & Research, Chennai, India. vinoth.lakshmanan@sriramachandra.edu.in.ORCID 0000-0002-7420-8459

Funding

DST 2021/001369
6 · The paper itself

Abstract

Biomarkers are molecules such as proteins, genes, or other substances that may be tested to determine the stage of the tumor in a patient. The role of prostate cancer biomarkers is pivotal and the combination of prostate cancer immunotherapy with efficient biomarkers has emerged as a beneficial treatment strategy and its use has increased rapidly. The two primary objectives of this current prostate cancer early detection programs were recognizing non-symptomatic individuals with prostate cancer requiring prostatic core biopsy and identifying men with prostate cancer who might benefit from definitive medical treatment. The progress that has been made so far in the identification of the biomarkers that can be used for the classification, prediction and prognostication of prostate cancer, and as major targets for its clinical intervention has been well summarized in this review.

Indexed as

Biomarkers, TumorProstatic NeoplasmsEarly Detection of CancerHumansMalePrognosisBiomarkers, TumorExosomesImmunotherapyLiquid biopsiesMetastasisProstatectomy

Identifiers

PMID39505512
PMCPMC11543649

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.