Evidence map›Paper›PMID 39505411›Full record

Observational studyGeriatrics & gerontology international2024

Associations among frailty conditions and pain indicators: Data from 22 356 European older adults.

Trinidad Sentandreu-Mañó, Elena Marques-Sule, Pallav Deka, José M Tomás, Leiver Andrés Romero Pintado, Leonie Klompstra, Hady Atef

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Geriatrics & gerontology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Trinidad Sentandreu-MañóDepartment of Physiotherapy, University of Valencia, Valencia, Spain.ORCID https://orcid.org/0000-0003-4405-0539
Elena Marques-SulePhysiotherapy in Motion, Multispeciality Research Group (PTin MOTION), Department of Physiotherapy, University of Valencia, Valencia, Spain.
Pallav DekaCollege of Nursing, Michigan State University, East Lansing, MI, USA.
José M TomásDepartment of Methodology for the Behavioral Sciences, University of Valencia, Valencia, Spain.
Leiver Andrés Romero PintadoDepartment of Physiotherapy, University of Valencia, Valencia, Spain.
Leonie KlompstraDepartment of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden.
Hady AtefSchool of Allied Health Professions (SAHP), Keele University, Staffordshire, UK.ORCID https://orcid.org/0000-0002-3089-2674

Funding

MCIN PID2021-124418OB-I00
6 · The paper itself

Abstract

aimRecent studies supported the presence of a relationship between pain and frailty, but more research is needed to highlight the pain-frailty association. The study aimed to investigate the prevalence and the influence of different pain indicators on frailty while controlling for age, sex and country.

methodsThis observational study used data from the sixth wave of the SHARE survey. A sample of 22 356 community-dwelling individuals aged >60 years from six European countries (Spain, Estonia, France, Greece, Czech Republic and Sweden) was analyzed. The pain was measured through assessment of medication used for joint pain or other types of pain, pain location, polypharmacy and pain level. Frailty was assessed with the modified Fried Frailty phenotype.

resultsPain indicators, especially widespread pain and pain severity, were significantly associated with prefrailty (odds ratio 3.30, 95% CI 2.40, 4.55; and odds ratio 0.61, 95% CI 0.51, 0.72) and frailty status (odds ratio 4.69, 95% CI 3.31, 6.67; and odds ratio 0.37, 95% CI 0.30, 0.44). Advancing age and female sex consistently correlated with increased prefrailty (odds ratio 1.06, 95% CI 1.05, 1.07; and odds ratio 1.36, 95% CI 1.22, 1.53) and frailty risk (odds ratio 1.11, 95% CI 1.10, 1.12; and odds ratio 1.71, 95% CI 1.48, 1.96). Country-specific differences emerged, with Spaniards showing higher odds ratios of prefrailty and frailty compared with Swedish, French and Czech individuals, whereas Greeks showed elevated odds ratios compared with Spaniards. The factors associated jointly explained 27.5% of the variance in frailty categories.

conclusionSignificant associations were identified, particularly with widespread pain and pain severity, highlighting their impact on frailty. Country-specific variations in frailty prevalence were observed, alongside consistent associations with advancing age and female sex. These findings provide valuable insights into the intricate interplay between pain and frailty, offering the potential for targeted interventions in older adults' care through tailored pain management strategies. Geriatr Gerontol Int 2024; 24: 1362-1369.

Indexed as

Frail ElderlyFrailtyGeriatric AssessmentAgedAged, 80 and overEuropeFemaleHumansIndependent LivingMaleMiddle AgedPainPain MeasurementPrevalenceagingEuropefrailtyolder adultspain

Identifiers

PMID39505411
PMCPMC11628897

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.