Evidence map›Paper›PMID 39505080›Full record

ArticlePhysiology & behavior2025

Walking economy and exercise efficiency in successful weight loss maintainers.

Seth A Creasy, Rebecca C Rosenberg, Danielle M Ostendorf, Ray Browning, Edward L Melanson, Zhaoxing Pan, Victoria A Catenacci

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiology & behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seth A CreasyDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Anschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, CO, USA. Electronic address: seth.creasy@cuanschutz.edu.
Rebecca C RosenbergDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Danielle M OstendorfDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Anschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Ray BrowningDepartment of Health and Exercise Science, Colorado State University, Ft. Collins, CO, USA.
Edward L MelansonDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Division of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Eastern Colorado VA Geriatric Research, Education, and Clinical Center, Aurora, CO, USA.
Zhaoxing PanDepartment of Biostatistics and Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Victoria A CatenacciDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Anschutz Health & Wellness Center at the University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
Research Training Program in Metabolism, Obesity and Type 2 DiabetesT32DK120521 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 2020 to 2026
$2.1M
Designing with dissemination in mind: Development and evaluation of a theory-based physical activity intervention using the Multiphase Optimization StrategyK01HL161417 · NHLBI · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Danielle M Ostendorf · 2022 to 2026
$834k
Linking temporal patterns of modifiable behaviors to weight loss outcomesK01HL145023 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CREASY, SETH A · 2019 to 2023
$820k
Energy Expenditure in Subjects Successful at Weight Loss MaintenanceK23DK078913 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CATENACCI, VICTORIA A · 2007 to 2011
$796k
Training the Next Generation of Innovative and Collaborative Patient-Oriented Researchers to Reduce Obesity and Improve Cardiometabolic HealthK24HL169755 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI VICTORIA A CATENACCI · 2023 to 2026
$504k
NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002535NHLBI NIH HHS K01 HL145023NHLBI NIH HHS K01 HL161417NHLBI NIH HHS K24 HL169755NIDDK NIH HHS K23 DK078913NIDDK NIH HHS P30 DK048520NIDDK NIH HHS T32 DK120521
6 · The paper itself

Abstract

purposeFollowing short-term weight loss, the energetic cost of transport decreases and exercise efficiency increases. Whether changes persist during long-term weight maintenance is unknown.

methodsWe compared walking economy and exercise efficiency in weight loss maintainers (WLM, maintaining ≥13.6 kg weight loss for ≥1 year), controls without obesity (NC, BMI similar to current BMI of WLM), and controls with overweight/obesity (OC, BMI similar to pre-weight loss BMI of WLM). Energy expenditure (EE) and respiratory quotient were measured using indirect calorimetry at rest, while standing, and during treadmill walking. Gross and net energetic cost of transport (J/kg/m) was measured during level treadmill walking at 0.75, 1.12, and 1.52 m/s. Gross, net, and delta efficiency (%) were measured during inclined treadmill walking (2 %, 4 %, and 6 % grade) and a constant speed (1.12 m/s).

resultsWLM (n = 32, BMI: 23.8 ± 2.3 kg/m

conclusionWLM had lower walking economy and greater walking efficiency compared to OC, but there were no differences between WLM and NC. Thus, individuals maintaining significant weight loss may be successful with long-term weight loss, in part, due to resistance against adaptive reductions in walking energetics.

Indexed as

Energy MetabolismObesityWalkingWeight LossAdultBody Mass IndexCalorimetry, IndirectExerciseExercise TestFemaleHumansMaleMiddle AgedOverweightOxygen ConsumptionCost of transportEnergeticsMuscle efficiencyObesity

Identifiers

PMID39505080
PMCPMC11684771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.