ArticleArquivos de neuro-psiquiatria2024
Aura and osmophobia are associated with the IL1A -889C > T (rs1800587) variant in migraine.
Article in Arquivos de neuro-psiquiatria, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Targeting glial-orchestrated neuroinflammation in migraine pathophysiology.The journal of headache and pain · 2026Review
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Authors and funding
8 authors.
Funding
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Abstract
backgroundMigraine belongs to the group of primary headaches, affecting 14.4% of the global population. The pathophysiological mechanisms of migraine involve the interplay between hypothalamic activation, cortical spreading depression, trigeminal stimulation, and inflammatory components with neurogenic inflammation or neuroinflammation.
objectiveTo assess the frequency of the
methodsWe conducted a case-control study involving 92 migraine patients and 88 healthy controls matched for age, sex, body mass index (BMI), and ethnicity. Demographic, anthropometric, and clinical data were obtained. The
resultsThe study comprised predominantly women and Caucasian individuals, with no significant differences in terms of age, sex, ethnicity, or BMI observed between the migraine and control groups. Within the migraine group, 57.6% had episodic migraines, and 45.7% experienced aura. The patients carrying the CT genotype showed stronger associations with the presence of aura (CT: 57.7%; TT: 27.5%;
conclusionThe
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