Evidence map›Paper›PMID 39504494›Full record

ArticleSleep2025

Tetrodotoxin-mediated inactivation of medial prefrontal cortex decreases wakefulness and rapid eye movement sleep, and increases slow-wave sleep in rat.

Trent Groenhout, Sumegha Ponnaluri, Lana Sharba, Tiecheng Liu, Amanda Nelson, Viviane S Hambrecht-Wiedbusch, Giancarlo Vanini, Dinesh Pal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Trent GroenhoutDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Sumegha PonnaluriDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Lana SharbaDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Tiecheng LiuDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Amanda NelsonDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Viviane S Hambrecht-WiedbuschDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Giancarlo VaniniDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.
Dinesh PalDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, United States.ORCID 0000-0003-1239-5057

Funding

Role of the Prefrontal Cortex in the Control of Arousal StatesR01GM111293 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER, PAL, DINESH · 2015 to 2022
$2.6M
NIGMS NIH HHS R01 GM111293NIH HHS R01 GM111293University of Michigan Medical School
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

prefrontal cortexrapid eye movement sleepslow-wave sleeptetrodotoxinwakefulness

Identifiers

PMID39504494
PMCPMC11893534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.