Evidence map›Paper›PMID 39504305›Full record

ArticleChemSusChem2025

Selective Modification of the Product Profile of Biocatalytic Hydrolyzed PET via Product-Specific Medium Engineering.

Tobias Heinks, Katrin Hofmann, Simon Last, Igor Gamm, Luise Blach, Ren Wei, Uwe T Bornscheuer, Christof Hamel, Jan von Langermann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tobias HeinksFaculty of Process and Systems Engineering, Institute of Chemistry, Biocatalytic Synthesis, Otto von Guericke University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.ORCID 0000-0003-3131-2106
Katrin HofmannDepartment of Applied Biosciences and Process Engineering, Anhalt University of Applied Sciences, Bernburger Straße 55, 06366, Koethen, Germany.
Simon LastFaculty of Process and Systems Engineering, Institute of Chemistry, Biocatalytic Synthesis, Otto von Guericke University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Igor GammFaculty of Process and Systems Engineering, Institute of Process Engineering, Chemical Process Engineering, Otto von Guericke University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Luise BlachFaculty of Process and Systems Engineering, Institute of Process Engineering, Chemical Process Engineering, Otto von Guericke University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.
Ren WeiInstitute of Biochemistry, Dept. of Biotechnology & Enzyme Catalysis, University of Greifswald, Felix-Hausdorff-Str.4, 17487, Greifswald, Germany.ORCID 0000-0003-3876-1350
Uwe T BornscheuerInstitute of Biochemistry, Dept. of Biotechnology & Enzyme Catalysis, University of Greifswald, Felix-Hausdorff-Str.4, 17487, Greifswald, Germany.ORCID 0000-0003-0685-2696
Christof HamelDepartment of Applied Biosciences and Process Engineering, Anhalt University of Applied Sciences, Bernburger Straße 55, 06366, Koethen, Germany.ORCID 0000-0001-9082-8095
Jan von LangermannFaculty of Process and Systems Engineering, Institute of Chemistry, Biocatalytic Synthesis, Otto von Guericke University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany.

Funding

Deutsche Forschungsgemeinschaft 450014604Deutsche Forschungsgemeinschaft 505185500Ministry for Science, Energy, Climate Protection and the Environment of the State of Saxony-Anhalt
6 · The paper itself

Abstract

Over the past years, enzymatic depolymerization of PET, one of the most widely used plastics worldwide, has become very efficient leading to the end products terephthalic acid (TPA) and ethylene glycol (EG) used for PET re-synthesis. Potent alternatives to these monomers are the intermediates BHET and MHET, the mono- and di-esters of TPA and EG which avoid total hydrolysis and can serve as single starting materials for direct re-polymerization. This study therefore aimed to selectively prepare those intermediates through reaction medium engineering during the biocatalytic hydrolysis of PET. After a comparative pre-screening of 12 PET-hydrolyzing enzymes, two of them (LCC

Indexed as

BiocatalysisPolyethylene TerephthalatesEthylene GlycolHydrolysisPhthalic AcidsEthylene GlycolPhthalic AcidsPolyethylene Terephthalatesterephthalic acidBHETBiocatalysisEnzymatic PET-HydrolysisEnzyme screeningMedium EngineeringMHETPETase

Identifiers

PMID39504305
PMCPMC11911963

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.