Evidence map›Paper›PMID 39503813›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2025

Cost-effectiveness and cost-utility analysis of a nurse-led, transitional care model to improve care coordination for patients with cardiovascular diseases: results from the "Cardiolotse" study.

Marie Coors, Wiebke Schüttig, Katrin C Reber, Harald Darius, Alfred Holzgreve, Sebastian Karmann, Anica Stürtz, Rebecca Zöller, Saskia Kropp, Petra Riesner and 1 more

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marie CoorsChair of Health Economics, TUM School of Medicine and Health, Technical University of Munich, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany. marie.coors@tum.de.ORCID http://orcid.org/0000-0002-6800-3326
Wiebke SchüttigChair of Health Economics, TUM School of Medicine and Health, Technical University of Munich, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany.
Katrin C ReberAOK Nordost-Die Gesundheitskasse, Health Services Management, Berlin, Germany.
Harald DariusVivantes-Netzwerk für Gesundheit GmbH, Berlin, Germany.
Alfred HolzgreveVivantes-Netzwerk für Gesundheit GmbH, Berlin, Germany.
Sebastian KarmannVivantes-Netzwerk für Gesundheit GmbH, Berlin, Germany.
Anica StürtzAOK Nordost-Die Gesundheitskasse, Health Services Management, Berlin, Germany.
Rebecca ZöllerAOK Nordost-Die Gesundheitskasse, Health Services Management, Berlin, Germany.
Saskia KroppChair of Health Economics, TUM School of Medicine and Health, Technical University of Munich, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany.
Petra RiesnerAOK Nordost-Die Gesundheitskasse, Health Services Management, Berlin, Germany.
Leonie SundmacherChair of Health Economics, TUM School of Medicine and Health, Technical University of Munich, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany.

Funding

Gemeinsame Bundesausschuss 01NVF17036
6 · The paper itself

Abstract

objectiveTo assess the 12-month cost-effectiveness of the nurse-led transitional care program "Cardiolotse" (CL) for patients with cardiovascular diseases compared to usual care (UC).

methodsA cost-effectiveness analysis (CEA) and cost-utility analysis (CUA) were conducted from the perspective of statutory health insurance (SHI), covering a time horizon of 12 months. Analyzed outcomes included the number of rehospitalizations and health-related quality of life (HRQoL). Total costs comprised program costs and the utilization of healthcare resources. Point estimates are presented as incremental cost-effectiveness ratios (ICERs) and incremental cost-utility ratios (ICURs). Sensitivity and subgroup analyses were conducted to illustrate uncertainty and provide insights into the impact mechanisms of the CL program.

resultsThe study population consisted of 2550 patients, with 1256 allocated to the intervention group and 1294 to the control group. Patients who received support from CLs experienced fewer rehospitalizations and lower inpatient costs from an SHI perspective, compared to the UC group. HRQoL assessments indicated higher utility values for CL patients at the 12-month follow-up. Total program costs amounted to €1454.65 per patient. The CEA and CUA demonstrate that the CL program is dominant compared to UC from the SHI perspective.

conclusionOur study shows that the CL program not only reduces the number of rehospitalizations and costs but increases HRQoL, resulting in a dominant ICER and ICUR. Further research is necessary to evaluate longer periods of time, different levels of care intensity, and perspectives of different healthcare stakeholders.

trial registrationGerman Clinical Trial Register DRKS00020424, 2020-06-18, retrospectively registered.

Indexed as

Cardiovascular DiseasesTransitional CareAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedPatient ReadmissionQuality-Adjusted Life YearsQuality of LifeCardiovascular diseaseCare coordinationCost-effectivenessEconomic evaluationHealth-related quality of lifeTransitional care

Identifiers

PMID39503813
PMCPMC12204867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.