Evidence map›Paper›PMID 39503784›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Exploring the longitudinal course of motor dexterity in first-episode psychosis: a 10-year follow-up.

Manuel Sevilla-Ramos, Valentina Ladera, Ricardo García-García, Benedicto Crespo-Facorro, Rosa Ayesa-Arriola

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Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Manuel Sevilla-RamosFaculty of Psychology, University of Salamanca, Salamanca, Spain.ORCID http://orcid.org/0000-0002-0861-4619
Valentina LaderaFaculty of Psychology, University of Salamanca, Salamanca, Spain.ORCID http://orcid.org/0000-0003-4075-4483
Ricardo García-GarcíaFaculty of Psychology, University of Salamanca, Salamanca, Spain.ORCID http://orcid.org/0000-0002-7106-4525
Benedicto Crespo-FacorroDepartment of Psychiatry, Hospital Universitario Virgen del Rocío, University of Sevilla, Sevilla, Spain.ORCID http://orcid.org/0000-0003-0033-7132
Rosa Ayesa-ArriolaBiomedical Research Networking Center for Mental Health (CIBERSAM), Health Institute Carlos III, Madrid, Spain. rayesa@humv.es.ORCID http://orcid.org/0000-0003-0570-5352

Funding

Instituto de Salud Carlos III MS18-Ayuda
6 · The paper itself

Abstract

This study aimed to examine longitudinal changes in motor dexterity (MD) performance in first episode of psychosis (FEP), focusing on diagnosis-specific trajectories. Participants were recruited from the project PAFIP in Spain (134 FEP, 84 HC). MD was assessed using the Grooved Pegboard Test at baseline and at 10-year follow-up. Clinical and premorbid data were collected for the patients. FEP participants were classified as having schizophrenia (SCZ) or other psychosis (OP) and compared with a group of healthy controls (HC). MD correlated significantly with age and intelligence in all participants. MD in SCZ patients was additionally correlated with premorbid adjustment and negative symptoms, whereas in the OP group the association was with antipsychotic dose. SCZ patients showed a slight decline in MD at follow-up, whereas the OP and HC groups remained stable. There may be different long-term trajectories of MD across diagnoses in FEP patients. Early developmental factors such as premorbid adaptation and cognitive function, together with age-related changes, may influence a mild decline in MD specifically in schizophrenia.

Indexed as

Motor SkillsPsychomotor PerformancePsychotic DisordersSchizophreniaAdolescentAdultDisease ProgressionFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleNeuropsychological TestsPsychiatric Status Rating ScalesYoung AdultCognitionMotor dexterityPsychomotor performancePsychotic disordersSchizophrenia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.