Evidence map›Paper›PMID 39503495›Full record

ArticleJournal of clinical microbiology2024

Evaluation of the QIAstat-Dx BCID GN and GPF kits for direct identification and antimicrobial resistance prediction from blood culture bottles.

Sally Ng, Chai Yuin Tan, Jing Yan Yah, Nur A'tikah Binte Osman, Ka Lip Chew

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sally NgDepartment of Laboratory Medicine, National University Hospital, , Singapore.
Chai Yuin TanDepartment of Laboratory Medicine, National University Hospital, , Singapore.
Jing Yan YahDepartment of Laboratory Medicine, National University Hospital, , Singapore.
Nur A'tikah Binte OsmanDepartment of Laboratory Medicine, National University Hospital, , Singapore.
Ka Lip ChewDepartment of Laboratory Medicine, National University Hospital, , Singapore.ORCID 0000-0002-4654-6434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid multiplex PCR kits have been used for rapid identification of blood culture isolates and prediction of antimicrobial resistance. We performed an evaluation of the QIAstat-Dx BCID GN and GPF research use only (RUO) kits on positive blood culture bottles using routine laboratory testing as the reference standard. Positive blood culture bottles between November 2023 and January 2024 were tested with QIAstat-Dx BCID GN and GPF kits based on initial Gram stain results and compared against routine identification and phenotypic susceptibility testing. A total of 174 monomicrobial blood cultures were included in the final analysis. The 174 monomicrobial blood cultures composed of 129 BCID GN tests and 45 BCID GPF tests. The majority of on-target Gram-negative organisms in monomicrobial cultures were identified. One IMPORTANCE: This is one of the first evaluations of the QIAstat BCID kit and demonstrates high levels of correlation for both identification and antimicrobial resistance prediction.

Indexed as

Blood CultureSensitivity and SpecificityAnti-Bacterial AgentsBacteremiaBacteriaDrug Resistance, BacterialGram-Negative BacteriaHumansMicrobial Sensitivity TestsMultiplex Polymerase Chain ReactionReagent Kits, DiagnosticAnti-Bacterial AgentsReagent Kits, Diagnosticbacteremiablood culture identification (BCID) panelsQIAstat-Dxrapid diagnostics

Identifiers

PMID39503495
PMCPMC11633170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.