Evidence map›Paper›PMID 39503238›Full record

ArticleEuropean journal of pain (London, England)2025

Chronic pain among primary fentanyl users: The concept of self-medication.

Jane J Kim, Dianah Hayati, Milad Zamany, Fiona Choi, Kerry Jang, Martha Ignaszewski, Pouya Azar, Michael Krausz

Abstract read
In one paragraph

Article in European journal of pain (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Pain Medicine and the Opioid Crisis: Time to Own Our Responsibility!European journal of pain (London, England) · 2026
    Article
  4. Chronic pain among primary fentanyl users: The concept of self-medication.European journal of pain (London, England) · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jane J KimFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0009-0006-7473-1617
Dianah HayatiFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Milad ZamanyFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Fiona ChoiFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Kerry JangFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Martha IgnaszewskiFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Pouya AzarFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.
Michael KrauszFaculty of Medicine, Department of Psychiatry, University of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic pain is among the leading causes of disability worldwide, of which only a small percentage of patients receive adequate treatment for. Non-prescribed opioid analgesics are commonly sought out in effort to alleviate unrelieved pain. This study assesses the prevalence and correlates of chronic pain among primary fentanyl users.

methodsA cross-sectional and structured survey was conducted with 200 adults who reported fentanyl as their drug of choice from a Vancouver acute care hospital. Presence and levels of chronic pain were determined through self-report.

resultsThe majority of participants (n = 130, 72.6%) reported having chronic pain in the past 6 months, with the mean level of pain on a typical day to be 7.6 out of a scale of 10 (SD = 1.9). Majority (n = 85, 65.4%) reported using street opioids to self-medicate, while only 9 (6.9%) reported that their chronic pain was unrelated. Regression analysis indicated that increasing age and co-use of cannabis and opioids were independent associated factors of chronic pain. Higher levels of reported pain on a typical day were further associated with age and self-medication.

conclusionsThe findings of this study demonstrate a significant association between self-medication and chronic pain among primary fentanyl users in British Columbia. For these individuals, inadequate pain relief may drive continued opioid use, which in turn may increase risks of treatment discontinuation and overdose. Appropriate pain management strategies are crucial to avoid opioid misuse and decrease the large societal burden caused by chronic pain. SIGNIFICANCE: Our work points to the high prevalence of self-reported chronic pain among individuals who primarily use fentanyl. Among those with self-reported fentanyl use and chronic pain, self-medication with street opioids was found to be common and associated with higher reported pain levels on a typical day. This highlights the need for pain management strategies to be integrated into opioid dependence treatment and more research in the overlap of pain and fentanyl use.

Indexed as

Analgesics, OpioidChronic PainFentanylSelf MedicationAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedOpioid-Related DisordersPrevalenceSelf ReportYoung AdultAnalgesics, OpioidFentanyl

Identifiers

PMID39503238
PMCPMC11610678

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.