Evidence map›Paper›PMID 39502969›Full record

ArticleCureus2024

Acquired Angioedema Post COVID-19 Infection: Can SARS-Cov-2 Induce Angioedema?

Misleydi Rios Rodriguez, Jake Singh, Kindness Nwakudu, Shannon Feely, Anila Khaliq, David Manna

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Misleydi Rios RodriguezFamily Medicine, Touro College of Osteopathic Medicine, Middletown, USA.
Jake SinghFamily Medicine, Touro College of Osteopathic Medicine, Middletown, USA.
Kindness NwakuduFamily Medicine, Touro College of Osteopathic Medicine, Middletown, USA.
Shannon FeelyFamily Medicine, Touro College of Osteopathic Medicine, Middletown, USA.
Anila KhaliqFamily Medicine, Garnet Health Medical Center, Middletown, USA.
David MannaBasic Biomedical Science, Touro College of Osteopathic Medicine, Middletown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ongoing research continues to uncover the long-term effects of post-COVID-19 illnesses. Patients with hereditary angioedema (HAE) are believed to have an elevated risk of contracting COVID-19 caused by SARS-CoV-2, potentially leading to increased frequency or more severe symptoms. This speculation is based on the understanding that COVID-19 enters cells through the angiotensin-converting enzyme 2 (ACE2) receptor. This report presents the case of a 37-year-old man with no significant medical history who presented to the clinic with what was initially thought to be an allergic reaction. He had experienced swelling in his lips, both upper extremities, and widespread urticaria, along with mild associated abdominal pain. While there is currently no conclusive evidence linking COVID-19 to the onset of HAE, a significant number of cases suggest a potential connection between post-COVID-19 angioedema and long-term angioedema. Subsequently, the patient experienced a second episode of angioedema flare-up aggravated by an upper respiratory infection.

Indexed as

angioedemacovid-19hereditary angioedemanon-respiratory symptoms post covidpost-covid

Identifiers

PMID39502969
PMCPMC11537483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.