Evidence map›Paper›PMID 39502884›Full record

ArticleArXiv2025

Dynamic glucose enhanced imaging using direct water saturation.

Linda Knutsson, Nirbhay N Yadav, Sajad Mohammed Ali, David Olayinka Kamson, Eleni Demetriou, Anina Seidemo, Lindsay Blair, Doris D Lin, John Laterra, Peter C M van Zijl

Abstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Linda KnutssonF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.ORCID 0000-0002-4263-113X
Nirbhay N YadavF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Sajad Mohammed AliDepartment of Medical Radiation Physics, Lund University, Lund, Sweden.ORCID 0000-0002-4707-8206
David Olayinka KamsonDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Eleni DemetriouF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Anina SeidemoDiagnostic Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.ORCID 0000-0002-0919-9680
Lindsay BlairDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Doris D LinRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
John LaterraDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Peter C M van ZijlF.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.

Funding

Development and Translation of D-glucose as a Diagnostic Agent for MRI of CancerR01EB034978 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Linda Knutsson, Peter CM Van Zijl · 2023 to 2026
$2.5M
State of the Art 3T Research ScannerS10OD021648 · OD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2016 to 2016
$2.0M
NIBIB NIH HHS R01 EB034978NIH HHS S10 OD021648
6 · The paper itself

Abstract

Purpose: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based linewidth ( Methods: To estimate the glucose-infusion-induced Results: In simulations, Conclusions: DS-DGE MRI is highly promising for assessing D-glucose uptake. Initial results in brain tumor patients show high-quality

Indexed as

CESTdirect saturation (DS)dynamic glucose enhanced (DGE) MRIglucoCESTZ-spectra

Identifiers

PMID39502884
PMCPMC11537340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.