Evidence map›Paper›PMID 39502883›Full record

ArticleCase reports in gastrointestinal medicine2024

VCTE Overestimates Liver Fibrosis due to Abdominal-Truncal Adiposity and Not Hepatic Steatosis: A Case Report.

Jordan S Woodard, Jena Velji-Ibrahim, Jay Alden, Gary A Abrams

Abstract readCase Reports
In one paragraph

Article in Case reports in gastrointestinal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jordan S WoodardUniversity of Kentucky Healthcare, Department of Medicine, Lexington, Kentucky, USA.ORCID https://orcid.org/0009-0007-9171-2300
Jena Velji-IbrahimPrisma Health-Upstate, Department of Medicine, Greenville, South Carolina, USA.ORCID https://orcid.org/0000-0002-5282-0727
Jay AldenPrisma Health-Upstate, Department of Pathology, Greenville, South Carolina, USA.ORCID https://orcid.org/0000-0003-4406-3903
Gary A AbramsPrisma Health-Upstate, Department of Medicine, Greenville, South Carolina, USA.ORCID https://orcid.org/0000-0001-8036-3861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibration-controlled transient elastography (VCTE) is used for the noninvasive assessment of liver fibrosis. We present a case of significant weight loss over 1 year, resulting in a marked improvement in liver stiffness suggesting a decrease in liver fibrosis from stage 4 (cirrhosis) to stage 2 (moderate fibrosis) notably without a change in the grade of hepatic steatosis. The improvement in two stages of fibrosis over this short time frame is due to the overestimation of liver stiffness in a subject with class 3 obesity and not due to the resolution of fibrosis. Therefore, this case highlights that BMI, due to excess subcutaneous abdominal adipose tissue and not intrahepatic lipid accumulation, can cause a significant overestimation of liver fibrosis with VCTE.

Identifiers

PMID39502883
PMCPMC11535426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.