ArticleFrontiers in medicine2024
Environmental triggers of pemphigus vulgaris and bullous pemphigoid: a case control study.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Trial
- The Immunological Intersection of Psoriasis and Autoimmune Diseases: Shared Pathways and Clinical Implications.Life (Basel, Switzerland) · 2026Review
- Incidence Trends and Severe in-Hospital Outcomes of Pemphigus Vulgaris: A Nationwide Cohort Study.The Journal of dermatology · 2026Article
- Non-COVID-19 Vaccinations and the Induction of Autoantibodies in Pemphigus Diseases: A Review of the Speculative Issue and Our Clinical-Laboratory Experience.Antibodies (Basel, Switzerland) · 2026Review
- Viral infections as triggers in autoimmune blistering diseases: A systematic review of associations and mechanisms.JAAD international · 2026Article
- Could vector-derived cadherin mimicry contribute to pemphigus vulgaris? An immunogenetic andFrontiers in immunology · 2026Article
- Expanding the Spectrum of Bullous Pemphigoid in Skin of Color.Indian dermatology online journal · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Previous case-control studies have suggested that environmental factors including exposure to pesticides and organic materials, diet and medications have an important role in the pathogenesis of pemphigus vulgaris. These studies lacked geographical population controls and had less than three controls per case. Objective: To identify environmental and occupational risk factors associated with the development of pemphigus vulgaris (PV) and bullous pemphigoid (BP). Method: Cases were patients with PV ( Results: Significant factors associated with PV included the daily consumption of leeks (odds ratio (OR) 3.6; Conclusion: Dietary factors containing thiol groups such as leeks, tomatoes, and mustard oil may be potential triggers for PV. High levels of mental stress, the use of supplementary medications such as calcium and multivitamins, and chemical cleaning products containing lime may be associated with an increased risk of developing both PV and BP. Lifestyle changes should be part of routine management for these patients.
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Registered trials
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